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B2VKT2

- TRPB_ERWT9

UniProt

B2VKT2 - TRPB_ERWT9

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Protein

Tryptophan synthase beta chain

Gene
trpB, ETA_16000
Organism
Erwinia tasmaniensis (strain DSM 17950 / Et1/99)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine By similarity.UniRule annotation

Catalytic activityi

L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. tryptophan synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciETAS465817:GI36-1659-MONOMER.
UniPathwayiUPA00035; UER00044.

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan synthase beta chain (EC:4.2.1.20)
Gene namesi
Name:trpB
Ordered Locus Names:ETA_16000
OrganismiErwinia tasmaniensis (strain DSM 17950 / Et1/99)
Taxonomic identifieri338565 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia
ProteomesiUP000001726: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Tryptophan synthase beta chainUniRule annotationPRO_1000095788Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei86 – 861N6-(pyridoxal phosphate)lysine By similarity

Proteomic databases

PRIDEiB2VKT2.

Interactioni

Subunit structurei

Tetramer of two alpha and two beta chains By similarity.

Protein-protein interaction databases

STRINGi465817.ETA_16000.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpB family.

Phylogenomic databases

eggNOGiCOG0133.
HOGENOMiHOG000161710.
KOiK01696.
OMAiEFMTLLQ.
OrthoDBiEOG6GFGH7.

Family and domain databases

HAMAPiMF_00133. Trp_synth_beta.
InterProiIPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
IPR006653. Trp_synth_b_CS.
IPR006654. Trp_synth_beta.
IPR023026. Trp_synth_beta/beta-like.
[Graphical view]
PANTHERiPTHR10314:SF3. PTHR10314:SF3. 1 hit.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF001413. Trp_syn_beta. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR00263. trpB. 1 hit.
PROSITEiPS00168. TRP_SYNTHASE_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2VKT2-1 [UniParc]FASTAAdd to Basket

« Hide

MTRLNPYFGE FGGMYVPQIL MPALLQLEDA FISAQSDPAF QAEFTDLLKN    50
YAGRPTALTR CLNLTKGSKT RLYLKREDLL HGGAHKTNQV LGQALLAKRM 100
GKKEIIAETG AGQHGVASAL ACALLGLKCR IYMGAKDIER QSPNLFRMRL 150
MGAEVIPVHS GSATLKDACN EALRDWSGSY ETAHYMLGTA AGPHPFPTIV 200
REFQRMIGEE TKAQILQQEG RLPDAVIACV GGGSNAIGMF ADFIDEPGVE 250
LIGVEPGGHG IESGEHGAPL KHGRVGIYFG MKSPMMQTAD GQIEESYSIS 300
AGLDFPSVGP QHAHLNSIGR ANYVSITDEE ALDAFKALCR SEGIIPALES 350
SHALAHALKM MREAPEKEQL LVVNLSGRGD KDIFTVHDIL TAKGEI 396
Length:396
Mass (Da):42,742
Last modified:July 1, 2008 - v1
Checksum:iAA359CCBBD7798BA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU468135 Genomic DNA. Translation: CAO96646.1.
RefSeqiYP_001907539.1. NC_010694.1.

Genome annotation databases

EnsemblBacteriaiCAO96646; CAO96646; ETA_16000.
GeneIDi6300215.
KEGGieta:ETA_16000.
PATRICi20429002. VBIErwTas9546_1673.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU468135 Genomic DNA. Translation: CAO96646.1 .
RefSeqi YP_001907539.1. NC_010694.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 465817.ETA_16000.

Proteomic databases

PRIDEi B2VKT2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAO96646 ; CAO96646 ; ETA_16000 .
GeneIDi 6300215.
KEGGi eta:ETA_16000.
PATRICi 20429002. VBIErwTas9546_1673.

Phylogenomic databases

eggNOGi COG0133.
HOGENOMi HOG000161710.
KOi K01696.
OMAi EFMTLLQ.
OrthoDBi EOG6GFGH7.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00044 .
BioCyci ETAS465817:GI36-1659-MONOMER.

Family and domain databases

HAMAPi MF_00133. Trp_synth_beta.
InterProi IPR001926. Trp_syn_b_sub_like_PLP_eny_SF.
IPR006653. Trp_synth_b_CS.
IPR006654. Trp_synth_beta.
IPR023026. Trp_synth_beta/beta-like.
[Graphical view ]
PANTHERi PTHR10314:SF3. PTHR10314:SF3. 1 hit.
Pfami PF00291. PALP. 1 hit.
[Graphical view ]
PIRSFi PIRSF001413. Trp_syn_beta. 1 hit.
SUPFAMi SSF53686. SSF53686. 1 hit.
TIGRFAMsi TIGR00263. trpB. 1 hit.
PROSITEi PS00168. TRP_SYNTHASE_BETA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic bacterium in the genus Erwinia."
    Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R., Geider K.
    Environ. Microbiol. 10:2211-2222(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17950 / Et1/99.

Entry informationi

Entry nameiTRPB_ERWT9
AccessioniPrimary (citable) accession number: B2VKT2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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