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Reviewed, UniProtKB/Swiss-Prot B2VK11 (ADD_ERWT9)

Last modified November 3, 2009. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase
Gene names
Name: add
Ordered Locus Names: ETA_17650
OrganismErwinia tasmaniensis (strain DSM 17950 / Et1/99) [Complete proteome] [HAMAP]
Taxonomic identifier338565 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia

Protein attributes

Sequence length332 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3. HAMAP MF_00540

Sequence similarities

Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine ribonucleoside monophosphate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionadenosine deaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 332332Adenosine deaminase HAMAP MF_00540
PRO_1000128847

Sites

Active site1971 Potential
Active site2451 Potential
Active site2781 Potential
Active site2791 Potential

Sequences

Sequence LengthMass (Da)Tools
B2VK11-1 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: E7A57711BC50B7F4

FASTA33235,708
        10         20         30         40         50         60 
MIDSQLPLTD IHRHLDGNIR AQTILDLGRE FNLTLPATTL AALRPHVQVI EAEPDLVSFL 

        70         80         90        100        110        120 
NKLDWGVKVL GSLDACRRVA LENVEDAARA GIHYAELRFS PGYMAMTHGL PVAGVVEAVI 

       130        140        150        160        170        180 
DGIRAGCAAH NIDVRLIGIM SRTFGEDACL RELDGLLAHR DGITALDLAG DELGFPGRRF 

       190        200        210        220        230        240 
LSHFNRARDA GLRITVHAGE AAGAESIWQA IRELGAERIG HGVKAVEDPA LMDFLAQEGI 

       250        260        270        280        290        300 
GIESCLTSNI QTSTVATLAD HPLKTFLNHG ILATINTDDP AVQGIEIEHE YHVAAPAAGL 

       310        320        330 
SVQQMRVAQE NGLKIAFLSE EEKAAVRARL AA 

« Hide

References

[1]"The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic bacterium in the genus Erwinia."
Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R., Geider K.
Environ. Microbiol. 10:2211-2222(2008) [PubMed: 18462403] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CU468135 Genomic DNA. Translation: CAO96811.1.
RefSeqYP_001907700.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6300718.
GenomeReviewsGene locus ETA_17650 in contig CU468135_GR.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAFLKKLDW.

Family and domain databases

HAMAPMF_00540.
[Tree]
InterProIPR006650. A/AMP_deam_AS.
IPR001365. A/AMP_deaminase.
IPR006330. A_deaminase.
[Graphical view]
PANTHERPTHR11409. A/AMP_deaminase. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. aden_deam. 1 hit.
PROSITEPS00485. A_DEAMINASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADD_ERWT9
AccessionPrimary (citable) accession number: B2VK11
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents