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Protein

Inositol 2-dehydrogenase

Gene

iolG

Organism
Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).UniRule annotation

Catalytic activityi

Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol 2-dehydrogenaseUniRule annotation (EC:1.1.1.18UniRule annotation)
Alternative name(s):
Myo-inositol 2-dehydrogenaseUniRule annotation
Short name:
MI 2-dehydrogenaseUniRule annotation
Gene namesi
Name:iolGUniRule annotation
Ordered Locus Names:ETA_32880
OrganismiErwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Taxonomic identifieri465817 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeErwinia
Proteomesi
  • UP000001726 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001873171 – 336Inositol 2-dehydrogenaseAdd BLAST336

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi465817.ETA_32880

Structurei

3D structure databases

ProteinModelPortaliB2VJP4
SMRiB2VJP4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Gfo/Idh/MocA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RJ5 Bacteria
COG0673 LUCA
HOGENOMiHOG000227439
KOiK00010
OMAiDHIRRCS
OrthoDBiPOG091H0FNG

Family and domain databases

HAMAPiMF_01671 IolG, 1 hit
InterProiView protein in InterPro
IPR023794 MI/DCI_dehydrogenase
IPR036291 NAD(P)-bd_dom_sf
IPR000683 Oxidoreductase_N
IPR004104 OxRdtase_C
PfamiView protein in Pfam
PF01408 GFO_IDH_MocA, 1 hit
PF02894 GFO_IDH_MocA_C, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

B2VJP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRLGVIGT GAIGQEHIRR CSKVLQGAQV VAVSDINVEG AKAALARIGI
60 70 80 90 100
DAQVFTDGYQ VVKSPDVDAL LVTSWDPTHE EFTLAAIAAG KPVFCEKPLA
110 120 130 140 150
MSAEGCRRIV DAEIKFGQRL VQVGFMRPYD SGYRALKNVI TQGEIGEPLM
160 170 180 190 200
LHCAHRNPTV PESYTTDMAI TNTLIHELDV LRWLTEDEYK SVQVVFPRST
210 220 230 240 250
SKTHGRLRDP QVVLFETRKG IRIDVEIFVN CAYGYDIQCE VVGENGIARL
260 270 280 290 300
PEPSAVQMRK DARLSTAILT DWKDRFIAAY DVELQAFIND ASAGKLNGPS
310 320 330
AWDGYAASVA ADACLKAQNS GGVEPIELPQ RPAFYR
Length:336
Mass (Da):36,868
Last modified:July 1, 2008 - v1
Checksum:iFC5DC044E407CDC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468135 Genomic DNA Translation: CAO98334.1
RefSeqiWP_012442960.1, NC_010694.1

Genome annotation databases

EnsemblBacteriaiCAO98334; CAO98334; ETA_32880
KEGGieta:ETA_32880

Similar proteinsi

Entry informationi

Entry nameiIOLG_ERWT9
AccessioniPrimary (citable) accession number: B2VJP4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: July 1, 2008
Last modified: March 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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