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B2VJ51 (DADA_ERWT9) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit

EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:ETA_15440
OrganismErwinia tasmaniensis (strain DSM 17950 / Et1/99) [Complete proteome] [HAMAP]
Taxonomic identifier338565 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia

Protein attributes

Sequence length433 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202

Cofactor

FAD By similarity. HAMAP MF_01202

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 433433D-amino acid dehydrogenase small subunit HAMAP MF_01202
PRO_1000138654

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
B2VJ51 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: E4C34ACCAB9C0EC3

FASTA43347,169
        10         20         30         40         50         60 
MRVVILGSGV VGVASAWYLA QAGHEVTVID RQPAPALETS AGNAGQISPG YAAPWAAPGV 

        70         80         90        100        110        120 
PLKAVKWMFQ RHAPLAIRLD GSRYQLEWMW QMLRNCDMRH YQQNKSRMVR IAEYSRDCLK 

       130        140        150        160        170        180 
ALREQTGIAY EGRQGGTLQL FRTAQQFESA AKDIAVLREA GVPYQLLEAA QLIEAEPALA 

       190        200        210        220        230        240 
ASQHKLSGGL RLPNDETGDC QLFTQRLAEM AMAAGVHFRF NTPVDALLQD ANQICGVQCG 

       250        260        270        280        290        300 
SERVTADAYV VALGSFSTEL LNHIVKIPVY PLKGYSLTIP ITDEKAAPLS TVLDETYKVA 

       310        320        330        340        350        360 
ITRFDNRIRV GGMAEIVGFN TQLLPARRKT LEMVVRDLYP HGGDIGRATF WSGLRPMTPD 

       370        380        390        400        410        420 
GTPVVGRTPL KNLYLNTGHG TLGWTMACGS GQLLADIISG RTPAISADDL SVIRYLPGFY 

       430 
PAPVRALHGV NVG 

« Hide

References

[1]"The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic bacterium in the genus Erwinia."
Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R., Geider K.
Environ. Microbiol. 10:2211-2222(2008) [PubMed: 18462403] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17950 / Et1/99.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU468135 Genomic DNA. Translation: CAO96590.1.
RefSeqYP_001907483.1. NC_010694.1.

3D structure databases

ProteinModelPortalB2VJ51.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6300395.
GenomeReviewsGene locus ETA_15440 in contig CU468135_GR.
PATRIC20428882. VBIErwTas9546_1614.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG729204.
OMAVDRQPAV.
ProtClustDBPRK00711.

Family and domain databases

HAMAPMF_01202. DadA.
[Tree]
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_ERWT9
AccessionPrimary (citable) accession number: B2VJ51
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families