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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei546UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:ETA_01330
OrganismiErwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Taxonomic identifieri465817 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeErwinia
Proteomesi
  • UP000001726 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001298331 – 883Phosphoenolpyruvate carboxylaseAdd BLAST883

Proteomic databases

PRIDEiB2VGA2

Interactioni

Protein-protein interaction databases

STRINGi465817.ETA_01330

Structurei

3D structure databases

SMRiB2VGA2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238648
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B2VGA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEQYSAMRS NVSMLGKLLG DTIKDALGEN ILDRVETIRK LSKSSRAGND
60 70 80 90 100
AHRQELLSTL QNLSNDELLP VARAFSQFLN LTNVAEQYHT ISPNGEGAKN
110 120 130 140 150
PELLLQTFQR LKQQPNLTEA AVCEALGSLS LELVLTAHPT EITRRTLIHK
160 170 180 190 200
LVEVNSCLKQ LDHNDLSDYE HAQIMRRLRQ LVAQAWHTDE IRKYRPSPVD
210 220 230 240 250
EAKWGFAVVE NSLWEGVPQF LRELNEQVEA AFGYTLPVDF VPVQFTSWMG
260 270 280 290 300
GDRDGNPNVT ADITRHVLQL SRWKATDLFL RDIAVLISEL SMSECTPEVR
310 320 330 340 350
ELCGNPEALE PYREIMKNLR SQLMSTQAYL AGRLKGERLT RPANLLIANE
360 370 380 390 400
QLWEPLYTCY QSLQACGMGI IANGQLLDTL RRVKCFGVPL VRIDIRQEST
410 420 430 440 450
RHTEAIAEIT RYLGLGDYES WSEADKQAFL IRELNSKRPL TPRQWEPSAD
460 470 480 490 500
TKEVLDTCRV AAEAPKGSIA AYVISMAKTP SDVLAVHLLL KEAGIDYAMP
510 520 530 540 550
VAPLFETLDD LNNANGVMSQ LLNIDWYRGL IQGKQMVMIG YSDSAKDAGV
560 570 580 590 600
MAASWAQYQA QDALIKTCEK AGITLTLFHG RGGSIGRGGA PAHAALLSQP
610 620 630 640 650
PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTGAILE ANLLPPPEPK
660 670 680 690 700
TEWIGIMERL SAVSCKMYRG YVREHAEFVP YFRSATPEQE LAKLPLGSRP
710 720 730 740 750
AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQQ VMEDGHQDQL
760 770 780 790 800
EAMCRDWPFF STRLGMLEMV FSKADLWLAE YYDQRLVDKS LWPLGKQLRD
810 820 830 840 850
QLESDIKAVL TIANDAHLMA DQPWIAESIA LRNVYTDPLN VLQAELLHRS
860 870 880
RQQEKAGGEP DARVEQALMV TIAGVAAGMR NTG
Length:883
Mass (Da):98,644
Last modified:July 1, 2008 - v1
Checksum:iE61CA1254C10C39D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468135 Genomic DNA Translation: CAO95179.1
RefSeqiWP_012439903.1, NC_010694.1

Genome annotation databases

EnsemblBacteriaiCAO95179; CAO95179; ETA_01330
KEGGieta:ETA_01330

Similar proteinsi

Entry informationi

Entry nameiCAPP_ERWT9
AccessioniPrimary (citable) accession number: B2VGA2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health