Reviewed, UniProtKB/Swiss-Prot B2VER0 (ARAA_ERWT9)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	ETA_17720

Organism

Erwinia tasmaniensis (strain DSM 17950 / Et1/99) [Complete proteome] [HAMAP]

Taxonomic identifier

338565 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Erwinia

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Subunit structure	Homohexamer By similarity.
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 501	501	L-arabinose isomerase HAMAP MF_00519		PRO_1000127606
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	333	1	Manganese By similarity
	Metal binding	350	1	Manganese By similarity
	Metal binding	450	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	B2VER0-1 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 98E1368865BEED5B	FASTA	501	55,549
	10 20 30 40 50 60 MTQINNRSVW FVIGTQHLYG VETLRQVERH GQQVVDSLNR SGILPFRLQI RPLVKTPDEA 70 80 90 100 110 120 LALCREANYD SECYGIMTWL HTFSPAKMWI GGLSVLHKPL LQFHTQFNAE IPWDSMDMDF 130 140 150 160 170 180 MNLNQTAHGG REFGFIGARM RLPHQVVTGH WQDERTLLRI GQWMRTAAAL QAGRQLKVAR 190 200 210 220 230 240 FGDNMREVAV TEGDKVAAQI QFGYSVNGWG VGDLVEVINQ VKDGDVNALV DEYESRYVFS 250 260 270 280 290 300 AAAAVGGAKR QNVLDAARIE LGIGRFLDDE GCRAFTTNFQ TLHGMTQLPG LAVQRLMQQG 310 320 330 340 350 360 YGFAGEGDWK TAALLHICKV MAGDLTGGTS FMEDYTYHFA PDNDLVLGSH MLEVCPSIAS 370 380 390 400 410 420 EARPLLDVQP LGIGGKADPA RLIFAAKAGR AVNASVIDMG DRFRLLVNVL DAVEPPRALP 430 440 450 460 470 480 KLPVARALWH AQPSLATASE AWILGGGAHH TVFSQALTVD DLRLYGEMLG IEVVVIDEQT 490 500 TLHGLRDALR WNEAYYRLNQ R

References

[1]

"The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic bacterium in the genus Erwinia." Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R., Geider K. Environ. Microbiol. 10:2211-2222(2008) [PubMed: 18462403] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CU468135 Genomic DNA. Translation: CAO96818.1.
RefSeq	YP_001907707.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6298491.
GenomeReviews	Gene locus ETA_17720 in contig CU468135_GR.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EVCPTIA.
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAA_ERWT9

Accession

Primary (citable) accession number: B2VER0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	November 3, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)