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B2VC92 (PNCB_ERWT9) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:ETA_21230
OrganismErwinia tasmaniensis (strain DSM 17950 / Et1/99) [Complete proteome] [HAMAP]
Taxonomic identifier338565 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeErwinia

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000129473

Sequences

Sequence LengthMass (Da)Tools
B2VC92 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 9B5B884278C4F1F0

FASTA40146,055
        10         20         30         40         50         60 
MTRHAAPILT TLLDTDAYKL HMQQAVFHRY YDVTVTAEFR CRGEDMLGIY ADELVQQIAN 

        70         80         90        100        110        120 
MASLTLTDNE FAYLSSLPFF KTDYLNWLRT FRYNPEQVTV QNLQGKLDIR ISGPWREVIL 

       130        140        150        160        170        180 
WEVPLLALIS EVVHRHRSPQ ITPEQAVSRL KSKLEQFKRL TCDLDMSRFR LMDFGTRRRF 

       190        200        210        220        230        240 
SHDVQLAVVS TLKQDFPWLV GSSNYDIARR LNIAPVGTQA HEWFQAHQQI SPTLENCQRA 

       250        260        270        280        290        300 
ALQAWLDEYP DRLGIALTDC ITTDAFLRDF GSEFAHAYQG LRHDSGDPFE WGEKAIAHYQ 

       310        320        330        340        350        360 
QLNIDPLSKT LVFSDNLDLD KAVGLYRHFE QRINVIFGIG TRLSCDIPQV KPLNIVIKLV 

       370        380        390        400 
ECNGKPVAKL SDSPGKTICH DKAFVRALRK AFDLPRVKKA S 

« Hide

References

[1]"The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic bacterium in the genus Erwinia."
Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R., Geider K.
Environ. Microbiol. 10:2211-2222(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17950 / Et1/99.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU468135 Genomic DNA. Translation: CAO97169.1.
RefSeqYP_001908047.1. NC_010694.1.

3D structure databases

ProteinModelPortalB2VC92.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING465817.ETA_21230.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAO97169; CAO97169; ETA_21230.
GeneID6299581.
KEGGeta:ETA_21230.
PATRIC20430083. VBIErwTas9546_2205.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycETAS465817:GI36-2191-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_ERWT9
AccessionPrimary (citable) accession number: B2VC92
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: March 19, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways