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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:ETA_21590
OrganismiErwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Taxonomic identifieri465817 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeErwinia
Proteomesi
  • UP000001726 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001319261 – 230Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST230

Interactioni

Protein-protein interaction databases

STRINGi465817.ETA_21590.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z. Bacteria.
COG2360. LUCA.
HOGENOMiHOG000102325.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiPOG091H045I.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

B2VC63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLAQLSHES LNFPPPDRAL REPNGLLAMG GDLSPQRLLN AYHRGIFPWF
60 70 80 90 100
AAGDPILWWS PDPRAILLPQ HFHLSRSMKR FHQKSPYRVT LNQRFRQVIE
110 120 130 140 150
GCASDRQEGT WITYEVKLAW QRLHELGHAH SIEVWQDEEL VGGMYGLALG
160 170 180 190 200
QIFCGESMFS QGENASKTAL LVFSRYFLQQ GGKLIDCQVL NPHTQSLGAQ
210 220 230
EIPRASYLSY LHSLAFRPLS SECWSPQRLF
Length:230
Mass (Da):26,344
Last modified:July 1, 2008 - v1
Checksum:iE7C4BB5EBF7BA970
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468135 Genomic DNA. Translation: CAO97205.1.
RefSeqiWP_012441875.1. NC_010694.1.

Genome annotation databases

EnsemblBacteriaiCAO97205; CAO97205; ETA_21590.
KEGGieta:ETA_21590.
PATRICi20430157. VBIErwTas9546_2242.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU468135 Genomic DNA. Translation: CAO97205.1.
RefSeqiWP_012441875.1. NC_010694.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi465817.ETA_21590.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAO97205; CAO97205; ETA_21590.
KEGGieta:ETA_21590.
PATRICi20430157. VBIErwTas9546_2242.

Phylogenomic databases

eggNOGiENOG4108R4Z. Bacteria.
COG2360. LUCA.
HOGENOMiHOG000102325.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiPOG091H045I.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLFTR_ERWT9
AccessioniPrimary (citable) accession number: B2VC63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: November 30, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.