B2VBU3 (6PGL_ERWT9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase
Short name=6-P-gluconolactonase
EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	ETA_22700

Organism

Erwinia tasmaniensis (strain DSM 17950 / Et1/99) [Complete proteome] [HAMAP]

Taxonomic identifier

338565 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Erwinia

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 330	330	6-phosphogluconolactonase HAMAP MF_01605		PRO_1000148158

Sequences

	Sequence		Length	Mass (Da)
	B2VBU3 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 958312E7CDC42D57	FASTA	330	36,085
	10 20 30 40 50 60 MKQVVYTASP ESQQIHAWQL NNEGALTLLQ VVDAPGQVQP MVVSPDKSFL YVGVRPDFRV 70 80 90 100 110 120 VAYQIDAEGK LKEAGHAPLP GSPTHISTDR QGRFIFVGSY NDACVSVTPI GENGLPGEPL 130 140 150 160 170 180 QVVKGLEGCH SANIDLNNQT LFVPALKQDR IALFSLDKQG KLTPRAQAEV KTRSGAGPRH 190 200 210 220 230 240 MAFHPNQRYA YSVNELDSSV DVWDISGDEV KKVQSVDALP EGFSDTRWAA DIHITPDGRH 250 260 270 280 290 300 LYSCDRTASN ITIFSISAEG SSLKVEGYQP TETQPRGFNI DHSGQYLVAA GQKSHHIEVY 310 320 330 KISADRGLLQ PLARYAVGQG PMWVVINKLD

References

[1]

"The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic bacterium in the genus Erwinia." Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R., Geider K. Environ. Microbiol. 10:2211-2222(2008) [PubMed: 18462403] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 17950 / Et1/99.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU468135 Genomic DNA. Translation: CAO97316.1.
RefSeq	YP_001908194.1. NC_010694.1.
3D structure databases
ProteinModelPortal	B2VBU3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6297907.
GenomeReviews	Gene locus ETA_22700 in contig CU468135_GR.
PATRIC	20430379. VBIErwTas9546_2353.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG741123.
OMA	TLDIMPA.
ProtClustDB	CLSK2543631.
Family and domain databases
HAMAP	MF_01605. 6P-gluconolactonase. [Tree]
InterPro	IPR022528. 6-phosphogluconolactonase_YbhE. IPR019405. Lactonase_7-beta_prop. IPR011045. N2O_reductase_N. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF10282. Lactonase. 1 hit. [Graphical view]
SUPFAM	SSF50974. N2O_reductase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_ERWT9

Accession

Primary (citable) accession number: B2VBU3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program