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B2V961 (B2V961_SULSY) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP MF_00137 RuleBase RU000613
EC=6.3.2.6 HAMAP MF_00137 RuleBase RU000613
Alternative name(s):
SAICAR synthetase HAMAP MF_00137
Gene names
Name:purC HAMAP MF_00137
Ordered Locus Names:SYO3AOP1_0856
OrganismSulfurihydrogenibium sp. (strain YO3AOP1) [Complete proteome] [HAMAP]
Taxonomic identifier436114 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Hydrogenothermaceae › Sulfurihydrogenibium

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137 RuleBase RU000613 SAAS SAAS018236

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137 RuleBase RU000613 SAAS SAAS018236

Sequence similarities

Belongs to the SAICAR synthetase family. HAMAP MF_00137 RuleBase RU004193

Sequences

Sequence LengthMass (Da)Tools
B2V961 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: F65EEB3BB4BB6D4A

FASTA23226,813
        10         20         30         40         50         60 
MEKLYEGKAK IVYQSESPNH VIIYFKDEAT AFNAQKKDVI EGKGILNNKI SSIFFTLLNQ 

        70         80         90        100        110        120 
AGVKTHFIKQ ISDREMLAYK TKIIPIEVVV RNLATGSIVK RLGIPEKTEF NPPLIEFYYK 

       130        140        150        160        170        180 
NDALGDPIIC YEHVLVMKLA TEEDVKTIKE MALKVNQILR DFLIKHDIIL VDFKLEFGKL 

       190        200        210        220        230 
YDGTIVVADE ISPDTCRFWD AKTGERMDKD RFRLNLGDLA KFYQEVLERI EK

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001080 Genomic DNA. Translation: ACD66484.1.
RefSeqYP_001931038.1. NC_010730.1.

3D structure databases

ProteinModelPortalB2V961.
SMRB2V961. Positions 2-231.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2V961.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6332270.
GenomeReviewsGene locus SYO3AOP1_0856 in contig CP001080_GR.
KEGGsul:SYO3AOP1_0856.
PATRIC23766501. VBISulSp94719_0887.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG306070.
OMAYKDDALG.
ProtClustDBPRK09362.

Family and domain databases

HAMAPMF_00137. SAICAR_synth.
[Tree]
InterProIPR013816. ATP_grasp_subdomain_2.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
Gene3DG3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KOK01923.
PANTHERPTHR11609. SAICAR_synt. 1 hit.
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsTIGR00081. PurC. 1 hit.
PROSITEPS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2V961_SULSY
AccessionPrimary (citable) accession number: B2V961
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info