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B2V7R0

- B2V7R0_SULSY

UniProt

B2V7R0 - B2V7R0_SULSY

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Protein

3-isopropylmalate dehydratase small subunit

Gene
leuD, SYO3AOP1_0338
Organism
Sulfurihydrogenibium sp. (strain YO3AOP1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate By similarity.UniRule annotation

Catalytic activityi

(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 3-isopropylmalate dehydratase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

Amino-acid biosynthesis, Branched-chain amino acid biosynthesis, Leucine biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciSSP436114:GI6I-354-MONOMER.
UniPathwayiUPA00048; UER00071.

Names & Taxonomyi

Protein namesi
Recommended name:
3-isopropylmalate dehydratase small subunitUniRule annotation (EC:4.2.1.33UniRule annotation)
Alternative name(s):
Alpha-IPM isomerase
Isopropylmalate isomerase
Gene namesi
Name:leuDUniRule annotation
Ordered Locus Names:SYO3AOP1_0338Imported
OrganismiSulfurihydrogenibium sp. (strain YO3AOP1)Imported
Taxonomic identifieri436114 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesHydrogenothermaceaeSulfurihydrogenibium
ProteomesiUP000001201: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. 3-isopropylmalate dehydratase complex Source: InterPro
Complete GO annotation...

Interactioni

Subunit structurei

Heterodimer of LeuC and LeuD By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi436114.SYO3AOP1_0338.

Structurei

3D structure databases

ProteinModelPortaliB2V7R0.
SMRiB2V7R0. Positions 1-161.

Family & Domainsi

Sequence similaritiesi

Belongs to the LeuD family. LeuD type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0066.
HOGENOMiHOG000222940.
KOiK01704.
OMAiYCMEDAR.
OrthoDBiEOG6PZXB8.

Family and domain databases

Gene3Di3.20.19.10. 1 hit.
HAMAPiMF_01032. LeuD_type2.
InterProiIPR015937. Acoase/IPM_deHydtase.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR000573. AconitaseA/IPMdHydase_ssu_swvl.
IPR011827. IsopropMal_deHydtase_ssu.
IPR011824. IsopropMal_deHydtase_ssu_bac.
[Graphical view]
PANTHERiPTHR11670. PTHR11670. 1 hit.
PfamiPF00694. Aconitase_C. 1 hit.
[Graphical view]
SUPFAMiSSF52016. SSF52016. 1 hit.
TIGRFAMsiTIGR02084. leud. 1 hit.
TIGR02087. LEUD_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

B2V7R0-1 [UniParc]FASTAAdd to Basket

« Hide

MIRGRVWKFK DDVDTDQIIP ARYLVTTDPK ELAKHVMEDA DPTFPSKVKE    50
GDILVAGKNF GCGSSREHAP LAIKGAGIAA VVAESFARIF FRNAINLGLL 100
IIESPEAARE AEEGDILEID INQGVIRNVT KNKEYKIKPL PENLQAILKA 150
GGLMEYAKEK IKNAS 165
Length:165
Mass (Da):18,146
Last modified:July 1, 2008 - v1
Checksum:i345698F080CC802A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001080 Genomic DNA. Translation: ACD65983.1.
RefSeqiYP_001930537.1. NC_010730.1.

Genome annotation databases

EnsemblBacteriaiACD65983; ACD65983; SYO3AOP1_0338.
GeneIDi6332711.
KEGGisul:SYO3AOP1_0338.
PATRICi23765383. VBISulSp94719_0350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001080 Genomic DNA. Translation: ACD65983.1 .
RefSeqi YP_001930537.1. NC_010730.1.

3D structure databases

ProteinModelPortali B2V7R0.
SMRi B2V7R0. Positions 1-161.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 436114.SYO3AOP1_0338.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD65983 ; ACD65983 ; SYO3AOP1_0338 .
GeneIDi 6332711.
KEGGi sul:SYO3AOP1_0338.
PATRICi 23765383. VBISulSp94719_0350.

Phylogenomic databases

eggNOGi COG0066.
HOGENOMi HOG000222940.
KOi K01704.
OMAi YCMEDAR.
OrthoDBi EOG6PZXB8.

Enzyme and pathway databases

UniPathwayi UPA00048 ; UER00071 .
BioCyci SSP436114:GI6I-354-MONOMER.

Family and domain databases

Gene3Di 3.20.19.10. 1 hit.
HAMAPi MF_01032. LeuD_type2.
InterProi IPR015937. Acoase/IPM_deHydtase.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR000573. AconitaseA/IPMdHydase_ssu_swvl.
IPR011827. IsopropMal_deHydtase_ssu.
IPR011824. IsopropMal_deHydtase_ssu_bac.
[Graphical view ]
PANTHERi PTHR11670. PTHR11670. 1 hit.
Pfami PF00694. Aconitase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52016. SSF52016. 1 hit.
TIGRFAMsi TIGR02084. leud. 1 hit.
TIGR02087. LEUD_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YO3AOP1.

Entry informationi

Entry nameiB2V7R0_SULSY
AccessioniPrimary (citable) accession number: B2V7R0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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