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B2V630 (AROA_SULSY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:SYO3AOP1_0004
OrganismSulfurihydrogenibium sp. (strain YO3AOP1) [Complete proteome] [HAMAP]
Taxonomic identifier436114 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Hydrogenothermaceae › Sulfurihydrogenibium

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4314313-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099758

Sequences

Sequence LengthMass (Da)Tools
B2V630 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: AE49A27B94466A04

FASTA43147,242
        10         20         30         40         50         60 
MEKTVKKVKR IEGSLRVPSD KSISHRAIIL SSLADGTSIV KNFLKAGDTL TTVNAYRKLG 

        70         80         90        100        110        120 
VEIVEKEGVY YVHGKGLDGL KEPDDLLDMG NSGTTTRLTL GVLAGFDFFA ALTGDDSLRK 

       130        140        150        160        170        180 
RPMKRVAEPL SKMGAKIDGR KDGNLLPISI RGGKLTGIDF FNEKMSAQVK SAILLAGLFA 

       190        200        210        220        230        240 
KGDTTVIEPV ISRDHTENML NSMGAYVSRE FTKDGYRVTV KKADKLNPIH INVPADPSSA 

       250        260        270        280        290        300 
AFFAAAASII SGSHIELKDV LINPTRDGFF RKLKEMGAKV EYKNKRDEAG EIVADIYISY 

       310        320        330        340        350        360 
HELKGVKVEP QEVPSMIDEI PLLAIIATQA EGETVITGAH ELRVKESDRI KSVIENFKRL 

       370        380        390        400        410        420 
GLEAEELPDG MIIRGKQKVK GGIVDSYKDH RIAMGFAILG LVSEEGITIK DADCVYISYP 

       430 
EFFNHLEKVS K

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: YO3AOP1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001080 Genomic DNA. Translation: ACD65655.1.
RefSeqYP_001930209.1. NC_010730.1.

3D structure databases

ProteinModelPortalB2V630.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2V630.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6332573.
GenomeReviewsGene locus SYO3AOP1_0004 in contig CP001080_GR.
KEGGsul:SYO3AOP1_0004.
PATRIC23764665. VBISulSp94719_0003.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_SULSY
AccessionPrimary (citable) accession number: B2V630
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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