B2V5I8 (B2V5I8_SULSY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134
Ordered Locus Names:	SYO3AOP1_1322

Organism

Sulfurihydrogenibium sp. (strain YO3AOP1) [Complete proteome] [HAMAP]

Taxonomic identifier

436114 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Hydrogenothermaceae › Sulfurihydrogenibium

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134 SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134 SAAS SAAS013798
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134 SAAS SAAS013798
Molecular function	Decarboxylase HAMAP MF_00134 SAAS SAAS013798 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2V5I8 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 3CD32FD7FCE58E26	FASTA	260	29,660
	10 20 30 40 50 60 MNILDKIIQT KREELENYTS QYLKHLEKLA IERNKKVLNF KKAISGKSIN IIAEVKKASP 70 80 90 100 110 120 SKGIIRHYFD PVDIAKSYEK NGAKAISVLT DKQYFQGDIA YLYQISTEVN IPLLRKDFII 130 140 150 160 170 180 DERQILEAYA YGADSYLLIA KVLDKESLKR LIDFGRELDM EPLVEVHSRE EGEKSVEAGA 190 200 210 220 230 240 RIIGINNRNL EDFTVDINLS KELAPYLKEI GSEVVVAESG LESRQQLLEL KNYQVDAFLI 250 260 GESLMKEADV GKKLREFIEG

References

[1]

"Complete and draft genome sequences of six members of the Aquificales." Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A. J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001080 Genomic DNA. Translation: ACD66932.1.
RefSeq	YP_001931486.1. NC_010730.1.
3D structure databases
ProteinModelPortal	B2V5I8.
ModBase	Search...
Protein-protein interaction databases
STRING	B2V5I8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6332674.
GenomeReviews	Gene locus SYO3AOP1_1322 in contig CP001080_GR.
KEGG	sul:SYO3AOP1_1322.
PATRIC	23767507. VBISulSp94719_1379.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG540956.
OMA	FFPEQVK.
ProtClustDB	PRK00278.
Family and domain databases
HAMAP	MF_00134_A. IGPS_A. [Tree] MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2V5I8_SULSY

Accession

Primary (citable) accession number: B2V5I8

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)