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Protein

Indole-3-glycerol phosphate synthase

Gene

SYO3AOP1_1322

Organism
Sulfurihydrogenibium sp. (strain YO3AOP1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseSAAS annotation, Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesisSAAS annotation

Enzyme and pathway databases

BioCyciSSP436114:GI6I-1370-MONOMER.
UniPathwayiUPA00035; UER00043.

Names & Taxonomyi

Protein namesi
Recommended name:
Indole-3-glycerol phosphate synthaseSAAS annotation (EC:4.1.1.48SAAS annotation)
Gene namesi
Ordered Locus Names:SYO3AOP1_1322Imported
OrganismiSulfurihydrogenibium sp. (strain YO3AOP1)Imported
Taxonomic identifieri436114 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesHydrogenothermaceaeSulfurihydrogenibium
ProteomesiUP000001201: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi436114.SYO3AOP1_1322.

Structurei

3D structure databases

ProteinModelPortaliB2V5I8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0134.
HOGENOMiHOG000230462.
KOiK01609.
OMAiDIAQSYA.
OrthoDBiEOG6WT8JX.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00134_A. IGPS_A.
MF_00134_B. IGPS_B.
InterProiIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
PROSITEiPS00614. IGPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2V5I8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNILDKIIQT KREELENYTS QYLKHLEKLA IERNKKVLNF KKAISGKSIN
60 70 80 90 100
IIAEVKKASP SKGIIRHYFD PVDIAKSYEK NGAKAISVLT DKQYFQGDIA
110 120 130 140 150
YLYQISTEVN IPLLRKDFII DERQILEAYA YGADSYLLIA KVLDKESLKR
160 170 180 190 200
LIDFGRELDM EPLVEVHSRE EGEKSVEAGA RIIGINNRNL EDFTVDINLS
210 220 230 240 250
KELAPYLKEI GSEVVVAESG LESRQQLLEL KNYQVDAFLI GESLMKEADV
260
GKKLREFIEG
Length:260
Mass (Da):29,660
Last modified:July 1, 2008 - v1
Checksum:i3CD32FD7FCE58E26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001080 Genomic DNA. Translation: ACD66932.1.
RefSeqiWP_012459991.1. NC_010730.1.
YP_001931486.1. NC_010730.1.

Genome annotation databases

EnsemblBacteriaiACD66932; ACD66932; SYO3AOP1_1322.
GeneIDi6332674.
KEGGisul:SYO3AOP1_1322.
PATRICi23767507. VBISulSp94719_1379.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001080 Genomic DNA. Translation: ACD66932.1.
RefSeqiWP_012459991.1. NC_010730.1.
YP_001931486.1. NC_010730.1.

3D structure databases

ProteinModelPortaliB2V5I8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi436114.SYO3AOP1_1322.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACD66932; ACD66932; SYO3AOP1_1322.
GeneIDi6332674.
KEGGisul:SYO3AOP1_1322.
PATRICi23767507. VBISulSp94719_1379.

Phylogenomic databases

eggNOGiCOG0134.
HOGENOMiHOG000230462.
KOiK01609.
OMAiDIAQSYA.
OrthoDBiEOG6WT8JX.

Enzyme and pathway databases

UniPathwayiUPA00035; UER00043.
BioCyciSSP436114:GI6I-1370-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00134_A. IGPS_A.
MF_00134_B. IGPS_B.
InterProiIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
PROSITEiPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: YO3AOP1Imported.

Entry informationi

Entry nameiB2V5I8_SULSY
AccessioniPrimary (citable) accession number: B2V5I8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: January 7, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.