Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B2V5F2 (F16PC_CLOBA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 3

Short name=FBPase class 3
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
Gene names
Name:fbp
Ordered Locus Names:CLH_2300
OrganismClostridium botulinum (strain Alaska E43 / Type E3) [Complete proteome] [HAMAP]
Taxonomic identifier508767 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length659 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP-Rule MF_01854

Cofactor

Manganese By similarity. HAMAP-Rule MF_01854

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_01854

Sequence similarities

Belongs to the FBPase class 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   LigandManganese
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 659659Fructose-1,6-bisphosphatase class 3 HAMAP-Rule MF_01854
PRO_0000363080

Sequences

Sequence LengthMass (Da)Tools
B2V5F2 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: DE7E785B19D73097

FASTA65976,709
        10         20         30         40         50         60 
MNNNDVEDIK KLKYFRLLAK QYPNIALAAT EIINLEAILN LPKGTEHFLS DIHGEYEPFV 

        70         80         90        100        110        120 
HVLRNGSGVV KRKIEDLFCK SLLESDIKSL ATLIYYPEQK LDIVLKEERN IDDWYKITLN 

       130        140        150        160        170        180 
RLIEICRFCS SKYTRSKVRK ALPADFAYII EELLHEQFNG IDKEEYYDRI ITTIIDIGRA 

       190        200        210        220        230        240 
KEFIIALSKL IQRMIIDRLH IIGDIYDRGP RPDIIIDTLM EYHSVDIQWG NHDMLWMGAA 

       250        260        270        280        290        300 
AGVRTCVANV LRISTRYANL DLVEEIYGIN LLPLATFALK YYRDDPCESF IPKVKEDDPA 

       310        320        330        340        350        360 
ANQEVDLVSK MHKAITILQF KLEKEIIDRR PEFELEERLL LDKIDYEKGT IILNGTEYKL 

       370        380        390        400        410        420 
NDNNFPTIDP KDPYKLTEEE SVLIDKLVYS FVNSDKLQKH VRFLFSKGNM YLKFNSNLLF 

       430        440        450        460        470        480 
HGCIPLDDDG NLKSMWIQGE EYESKRLLEK FDSLSREGYF EKVGSEEKTY GMDIMWYLWT 

       490        500        510        520        530        540 
GPVSPLFGKK KMATFERYFI DDEIAHIEQK TGYYKLRDRE EMCDMILREF GLDPSESRII 

       550        560        570        580        590        600 
NGHVPVKKKN GESPIKANGK MIVIDGGFSK AYQKQTGIAG YTLIYNSYGL QLVSHEHFSS 

       610        620        630        640        650 
TEESIMKEKD ILSTTLVVEQ KLKRKTVEDT DIGKELQVQI KDLKELLLIY RKGIIKEIR 

« Hide

References

[1]"Complete genome sequence of Clostridium botulinum E3 str. Alaska E43."
Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Alaska E43 / Type E3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001078 Genomic DNA. Translation: ACD52126.1.
RefSeqYP_001921681.1. NC_010723.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING508767.CLH_2300.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD52126; ACD52126; CLH_2300.
GeneID6317362.
KEGGcbt:CLH_2300.
PATRIC19420857. VBICloBot115804_2220.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3855.
HOGENOMHOG000285784.
KOK04041.
OMASYGMQLV.
OrthoDBEOG6R2GX7.
ProtClustDBCLSK876712.

Enzyme and pathway databases

BioCycCBOT508767:GHKO-2292-MONOMER.
UniPathwayUPA00138.

Family and domain databases

HAMAPMF_01854. FBPase_class3.
InterProIPR009164. FBPtase_class3.
[Graphical view]
PfamPF06874. FBPase_2. 1 hit.
[Graphical view]
PIRSFPIRSF000906. FBPtase_Bacill. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF16PC_CLOBA
AccessionPrimary (citable) accession number: B2V5F2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 1, 2008
Last modified: April 16, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways