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Protein

Fructose-1,6-bisphosphatase class 3

Gene

fbp

Organism
Clostridium botulinum (strain Alaska E43 / Type E3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.UniRule annotation

Cofactori

Mn2+UniRule annotation

Pathwayi

GO - Molecular functioni

  1. fructose 1,6-bisphosphate 1-phosphatase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciCBOT508767:GHKO-2292-MONOMER.
UniPathwayiUPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-1,6-bisphosphatase class 3UniRule annotation (EC:3.1.3.11UniRule annotation)
Short name:
FBPase class 3UniRule annotation
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3UniRule annotation
Gene namesi
Name:fbpUniRule annotation
Ordered Locus Names:CLH_2300
OrganismiClostridium botulinum (strain Alaska E43 / Type E3)
Taxonomic identifieri508767 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001738 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 659659Fructose-1,6-bisphosphatase class 3PRO_0000363080Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi508767.CLH_2300.

Family & Domainsi

Sequence similaritiesi

Belongs to the FBPase class 3 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3855.
HOGENOMiHOG000285784.
KOiK04041.
OMAiAKMHKAI.
OrthoDBiEOG6R2GX7.

Family and domain databases

Gene3Di3.60.21.10. 4 hits.
HAMAPiMF_01854. FBPase_class3.
InterProiIPR009164. FBPtase_class3.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF06874. FBPase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000906. FBPtase_Bacill. 1 hit.
SUPFAMiSSF56300. SSF56300. 4 hits.

Sequencei

Sequence statusi: Complete.

B2V5F2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNNDVEDIK KLKYFRLLAK QYPNIALAAT EIINLEAILN LPKGTEHFLS
60 70 80 90 100
DIHGEYEPFV HVLRNGSGVV KRKIEDLFCK SLLESDIKSL ATLIYYPEQK
110 120 130 140 150
LDIVLKEERN IDDWYKITLN RLIEICRFCS SKYTRSKVRK ALPADFAYII
160 170 180 190 200
EELLHEQFNG IDKEEYYDRI ITTIIDIGRA KEFIIALSKL IQRMIIDRLH
210 220 230 240 250
IIGDIYDRGP RPDIIIDTLM EYHSVDIQWG NHDMLWMGAA AGVRTCVANV
260 270 280 290 300
LRISTRYANL DLVEEIYGIN LLPLATFALK YYRDDPCESF IPKVKEDDPA
310 320 330 340 350
ANQEVDLVSK MHKAITILQF KLEKEIIDRR PEFELEERLL LDKIDYEKGT
360 370 380 390 400
IILNGTEYKL NDNNFPTIDP KDPYKLTEEE SVLIDKLVYS FVNSDKLQKH
410 420 430 440 450
VRFLFSKGNM YLKFNSNLLF HGCIPLDDDG NLKSMWIQGE EYESKRLLEK
460 470 480 490 500
FDSLSREGYF EKVGSEEKTY GMDIMWYLWT GPVSPLFGKK KMATFERYFI
510 520 530 540 550
DDEIAHIEQK TGYYKLRDRE EMCDMILREF GLDPSESRII NGHVPVKKKN
560 570 580 590 600
GESPIKANGK MIVIDGGFSK AYQKQTGIAG YTLIYNSYGL QLVSHEHFSS
610 620 630 640 650
TEESIMKEKD ILSTTLVVEQ KLKRKTVEDT DIGKELQVQI KDLKELLLIY

RKGIIKEIR
Length:659
Mass (Da):76,709
Last modified:July 1, 2008 - v1
Checksum:iDE7E785B19D73097
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001078 Genomic DNA. Translation: ACD52126.1.
RefSeqiYP_001921681.1. NC_010723.1.

Genome annotation databases

EnsemblBacteriaiACD52126; ACD52126; CLH_2300.
KEGGicbt:CLH_2300.
PATRICi19420857. VBICloBot115804_2220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001078 Genomic DNA. Translation: ACD52126.1.
RefSeqiYP_001921681.1. NC_010723.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi508767.CLH_2300.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACD52126; ACD52126; CLH_2300.
KEGGicbt:CLH_2300.
PATRICi19420857. VBICloBot115804_2220.

Phylogenomic databases

eggNOGiCOG3855.
HOGENOMiHOG000285784.
KOiK04041.
OMAiAKMHKAI.
OrthoDBiEOG6R2GX7.

Enzyme and pathway databases

UniPathwayiUPA00138.
BioCyciCBOT508767:GHKO-2292-MONOMER.

Family and domain databases

Gene3Di3.60.21.10. 4 hits.
HAMAPiMF_01854. FBPase_class3.
InterProiIPR009164. FBPtase_class3.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF06874. FBPase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000906. FBPtase_Bacill. 1 hit.
SUPFAMiSSF56300. SSF56300. 4 hits.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Clostridium botulinum E3 str. Alaska E43."
    Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Alaska E43 / Type E3.

Entry informationi

Entry nameiF16PC_CLOBA
AccessioniPrimary (citable) accession number: B2V5F2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 1, 2008
Last modified: April 1, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.