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B2V184 (DEOC_CLOBA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase
Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:deoC
Ordered Locus Names:CLH_0702
OrganismClostridium botulinum (strain Alaska E43 / Type E3) [Complete proteome] [HAMAP]
Taxonomic identifier508767 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114

Subcellular location

Cytoplasm By similarity HAMAP MF_00114.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processdeoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221Deoxyribose-phosphate aldolase HAMAP MF_00114
PRO_1000094839

Sites

Active site1531Schiff-base intermediate with acetaldehyde By similarity
Active site1821 By similarity

Sequences

Sequence LengthMass (Da)Tools
B2V184 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 0BA6F7A175D47BD3

FASTA22124,071
        10         20         30         40         50         60 
MNNAEILKHV DHTLLKPVAT WDDIKKICDE SIEYNTASIC IPACYISRIH ETYGDKINIC 

        70         80         90        100        110        120 
TVVGFPLGYS STEGKIAETK QALADGANEI DMVINISDVK NKAYDKVTEE IRALKEVVGN 

       130        140        150        160        170        180 
KILKVIIETC YLTEEEKIAM CKAVTEAGAD YIKTSTGFGT GGATLEDIKL FKKHIGPNVK 

       190        200        210        220 
IKAAGGVSTV EDLNMFINEG CDRLGTSRAV GLLKGEETQG Y

« Hide

References

[1]"Complete genome sequence of Clostridium botulinum E3 str. Alaska E43."
Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Alaska E43 / Type E3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001078 Genomic DNA. Translation: ACD52720.1.
RefSeqYP_001920097.1. NC_010723.1.

3D structure databases

ProteinModelPortalB2V184.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2V184.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6318556.
GenomeReviewsGene locus CLH_0702 in contig CP001078_GR.
KEGGcbt:CLH_0702.
PATRIC19417666. VBICloBot115804_0631.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG636421.
OMAEEKIAMC.
ProtClustDBPRK00507.

Family and domain databases

HAMAPMF_00114. DeoC_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/AroFGH_arch.
IPR022979. Deoxyribose_phosphate_aldo_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01619.
PANTHERPTHR10889. DeoC. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. DeoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_CLOBA
AccessionPrimary (citable) accession number: B2V184
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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