B2V0W4 (B2V0W4_CLOBA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL ACD51209.1
EC=1.5.1.3 EMBL ACD51209.1

Gene names

Name:	folA EMBL ACD51209.1
Ordered Locus Names:	CLH_3228

Organism

Clostridium botulinum (strain Alaska E43 / Type E3) [Complete proteome] [HAMAP]

Taxonomic identifier

508767 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	164 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ACD51209.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2V0W4 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 089198338D204127	FASTA	164	19,105
	10 20 30 40 50 60 MLSIIVAIAK NNVIGNDNKL IWHISEDLKR FKEITSGKTI VMGRKTFESL PGVLPNRKHI 70 80 90 100 110 120 ILTRDKNFKV NSECVEIIYD FDELLNKYKN SDTEVFIIGG GEIYKQLLPH TNKLYLTKIN 130 140 150 160 KDFDGDTYFP QINYDDFKVD YKSDIITDEK SKLEYNFINL SRLS

References

[1]	"Complete genome sequence of Clostridium botulinum E3 str. Alaska E43." Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001078 Genomic DNA. Translation: ACD51209.1.
RefSeq	YP_001922593.1. NC_010723.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2V0W4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6317990.
GenomeReviews	Gene locus CLH_3228 in contig CP001078_GR.
KEGG	cbt:CLH_3228.
PATRIC	19422697. VBICloBot115804_3128.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG665708.
OMA	APNTFGY.
ProtClustDB	CLSK2327306.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2V0W4_CLOBA

Accession

Primary (citable) accession number: B2V0W4

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)