Reviewed, UniProtKB/Swiss-Prot B2V049 (GLGA_CLOBA)

Names and origin

Protein names

Recommended name:
    Glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	CLH_3166

Organism

Clostridium botulinum (strain Alaska E43 / Type E3) [Complete proteome] [HAMAP]

Taxonomic identifier

508767 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	478 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity.
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 478	478	Glycogen synthase HAMAP MF_00484		PRO_1000126061
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	B2V049-1 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: D9BA37E2E4E34AD7	FASTA	478	55,860
	10 20 30 40 50 60 MRVLFVASEA HPFIKSGGLG DVAGALPKEL ARKGVDVRVV IPKYREINNE LKNKLRFNKW 70 80 90 100 110 120 FNVDVGWRNQ YCGILEYEYD GVIYYFVDNE YYFSRGGMYG HYDDAERFAF FDRAVLDMIK 130 140 150 160 170 180 QLDWKPNIIH CNDWQTGMIP VLLKLEYMRK DMFYWDIKSV FSIHNIAFQG VFDPVILPEL 190 200 210 220 230 240 FGYDYEQYTN TNLKFDDGVG FMKGAINYSD MITTVSYSYA EEIKTPEFGE RLDWLLREKS 250 260 270 280 290 300 YMLRGILNGI DYDEFNPKND NLINKNYDVN NINDKYENKR NLQSELGLNV NENIPIIAMV 310 320 330 340 350 360 TRLTSQKGLD LLVNISERLL QNDIQLVIVG TGDKHYEDHF KWLDYKYGNK VSANIRFDNN 370 380 390 400 410 420 LAHKVYAASD MFLMPSLFEP CGLGQLIALR YGSIPIVRET GGLKDTIRAY NEYTGEGNGF 430 440 450 460 470 SFYNYNADEL LHIIEYALKI YYDKNKWSNL VKNAMNSNNS WSKSADEYLN MYKELSYR

References

[1]	"Complete genome sequence of Clostridium botulinum E3 str. Alaska E43." Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001078 Genomic DNA. Translation: ACD53157.1.
RefSeq	YP_001922535.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6319896.
GenomeReviews	Gene locus CLH_3166 in contig CP001078_GR.
KEGG	cbt:CLH_3166.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	YQGPWRW.
Family and domain databases
HAMAP	MF_00484. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Glyco_transf_5. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_CLOBA

Accession

Primary (citable) accession number: B2V049

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)