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B2UZ17

- G6PI_CLOBA

UniProt

B2UZ17 - G6PI_CLOBA

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, CLH_0389
Organism
Clostridium botulinum (strain Alaska E43 / Type E3)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei312 – 3121 By similarity
Active sitei426 – 4261 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCBOT508767:GHKO-387-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:CLH_0389
OrganismiClostridium botulinum (strain Alaska E43 / Type E3)
Taxonomic identifieri508767 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001738: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Glucose-6-phosphate isomeraseUniRule annotationPRO_1000125707Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi508767.CLH_0389.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiGVESYKR.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2UZ17-1 [UniParc]FASTAAdd to Basket

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MKKGLTLDLS KTQAFVKDYE LDYMEGMVKD SHDRLHSKTG QGNDFLGWID    50
LPVDYDKEEF ARIKKAAEKI QSDSDVLVVI GIGGSYLGAR AAIEMLTSNF 100
HNVLDDNKRK VPKIFYAGNN ISSTYMAELL EAIDGKDVSV NVISKSGTTT 150
EPAIAFRIFK SYLEKKYGVE EARKRIYATT DKSRGALKSL ADAEGYETFV 200
IPDDVGGRFT VLTPVGLLPI AVAGINIDEM MQGAADARES YSNPSLKEND 250
CYKYAVTRNA LYNKGKEIEV LVNYEPCIHY FNEWWKQLYG ESEGKDKKGL 300
FPAAVDFSTD LHSMGQYIQD GRRNLFETVI NVEKARKEIT IEFSEGDLDG 350
LNFLTGKTMD FVNNKAFQGT LLAHNDGEVP NMVLNVPELS PYYFGHMVYF 400
FEKACGISGY LLGINPFDQP GVEAYKKNMF ALLGKPGYED MKDELEKRL 449
Length:449
Mass (Da):50,384
Last modified:July 1, 2008 - v1
Checksum:i01F2246A20935D47
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001078 Genomic DNA. Translation: ACD53102.1.
RefSeqiYP_001919822.1. NC_010723.1.

Genome annotation databases

EnsemblBacteriaiACD53102; ACD53102; CLH_0389.
GeneIDi6320501.
KEGGicbt:CLH_0389.
PATRICi19417048. VBICloBot115804_0355.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001078 Genomic DNA. Translation: ACD53102.1 .
RefSeqi YP_001919822.1. NC_010723.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 508767.CLH_0389.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD53102 ; ACD53102 ; CLH_0389 .
GeneIDi 6320501.
KEGGi cbt:CLH_0389.
PATRICi 19417048. VBICloBot115804_0355.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi GVESYKR.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CBOT508767:GHKO-387-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Clostridium botulinum E3 str. Alaska E43."
    Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Alaska E43 / Type E3.

Entry informationi

Entry nameiG6PI_CLOBA
AccessioniPrimary (citable) accession number: B2UZ17
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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