Reviewed, UniProtKB/Swiss-Prot B2UX89 (MURI_CLOBA)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	CLH_0058

Organism

Clostridium botulinum (strain Alaska E43 / Type E3) [Complete proteome] [HAMAP]

Taxonomic identifier

508767 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	258 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity.
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 258	258	Glutamate racemase HAMAP MF_00258		PRO_1000114036

Sequences

	Sequence		Length	Mass (Da)
	B2UX89-1 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 839A4D977BDCFC2D	FASTA	258	28,969
	10 20 30 40 50 60 MDKKNRPIGF FDSGVGGLSV MKEAIRLMPN ENYIYFGDSK NAPYGIKTVE EVRTLTFNAV 70 80 90 100 110 120 ESLLEKNVKA IVVACNTATS AAIDLVRSKY KNIPIIGIEP ALKLATKYNR KGNIIIMATP 130 140 150 160 170 180 MTLKEKKFKS LMEKYGENYD IVSLPCAKLV EFIEHGILSG EELEEYLKEK FKSYKNNDIG 190 200 210 220 230 240 VVVLGCTHYP FIKETLYKVI DKDIPIIDGG LGTSQELRRR LEEKNLLNTE DKKGSITIIN 250 SNGSEKMIEL SKKLIESS

References

[1]	"Complete genome sequence of Clostridium botulinum E3 str. Alaska E43." Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001078 Genomic DNA. Translation: ACD50964.1.
RefSeq	YP_001919512.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6317953.
GenomeReviews	Gene locus CLH_0058 in contig CP001078_GR.
KEGG	cbt:CLH_0058.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	AIWATPA.
Family and domain databases
HAMAP	MF_00258. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_CLOBA

Accession

Primary (citable) accession number: B2UX89

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 1, 2008
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)