B2UX18 (B2UX18_CLOBA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosyl-ATP pyrophosphatase HAMAP MF_01020
Short name=PRA-PH HAMAP MF_01020
EC=3.6.1.31 HAMAP MF_01020

Gene names

Name:	hisE HAMAP MF_01020 EMBL ACD54096.1
Ordered Locus Names:	CLH_2623

Organism

Clostridium botulinum (strain Alaska E43 / Type E3) [Complete proteome] [HAMAP]

Taxonomic identifier

508767 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate. HAMAP MF_01020 SAAS SAAS008179
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. HAMAP MF_01020 SAAS SAAS008179
Subcellular location	Cytoplasm By similarity HAMAP MF_01020.
Sequence similarities	Belongs to the PRA-PH family. HAMAP MF_01020

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01020 SAAS SAAS008179
Cellular component	Cytoplasm HAMAP MF_01020
Ligand	ATP-binding HAMAP MF_01020 SAAS SAAS008179 Nucleotide-binding
Molecular function	Hydrolase HAMAP MF_01020 SAAS SAAS008179 EMBL ACD54096.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosyl-ATP diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2UX18 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 27410B83DA6E0D43	FASTA	108	12,579
	10 20 30 40 50 60 MENEIENLYN TILERKISGE NGSYTNYLFA QGINKILKKV GEECTEVIIS SKENNREEQV 70 80 90 100 NEICDLTYHI LVLMAELNIP LEDIKNELKK RSEKINNFKG ERKPIKGY

References

[1]	"Complete genome sequence of Clostridium botulinum E3 str. Alaska E43." Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001078 Genomic DNA. Translation: ACD54096.1.
RefSeq	YP_001922003.1. NC_010723.1.
3D structure databases
ProteinModelPortal	B2UX18.
ModBase	Search...
Protein-protein interaction databases
STRING	B2UX18.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6319724.
GenomeReviews	Gene locus CLH_2623 in contig CP001078_GR.
KEGG	cbt:CLH_2623.
PATRIC	19421497. VBICloBot115804_2539.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646527.
OMA	EMRRREN.
ProtClustDB	CLSK2327033.
Family and domain databases
HAMAP	MF_01020. HisE. [Tree]
InterPro	IPR008179. PRib-ATP_PPHydrolase. IPR021130. PRib-ATP_PPHydrolase-like. [Graphical view]
KO	K01523.
Pfam	PF01503. PRA-PH. 1 hit. [Graphical view]
TIGRFAMs	TIGR03188. Histidine_hisI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2UX18_CLOBA

Accession

Primary (citable) accession number: B2UX18

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)