B2UWE6 (DCD_CLOBA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CLH_2400

Organism

Clostridium botulinum (strain Alaska E43 / Type E3) [Complete proteome] [HAMAP]

Taxonomic identifier

508767 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	173 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 173	173	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000189824

Sequences

	Sequence		Length	Mass (Da)
	B2UWE6 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: ACF2D04184C30D3F	FASTA	173	19,973
	10 20 30 40 50 60 MILSGKEILK HIGEDIIIEP FSEERINPNS YNLTLFNELL VYKNDTLDMK IPNETEKLII 70 80 90 100 110 120 PEEGLLLEPG KLYLGRTNEF TQTNKYVPML EGRSSTGRLG LFIHVTAGFG DIGFAGYWTL 130 140 150 160 170 EIFCVQPIRI YPNTEICQIY YHNIDGEYDL YNSGKYQNNN GIQPSLMYKD FEK

References

[1]

"Complete genome sequence of Clostridium botulinum E3 str. Alaska E43." Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Alaska E43 / Type E3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001078 Genomic DNA. Translation: ACD52759.1.
RefSeq	YP_001921781.1. NC_010723.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2UWE6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6317310.
GenomeReviews	Gene locus CLH_2400 in contig CP001078_GR.
KEGG	cbt:CLH_2400.
PATRIC	19421053. VBICloBot115804_2318.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
OMA	HQTAGWI.
ProtClustDB	PRK00416.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
KO	K01494.
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CLOBA

Accession

Primary (citable) accession number: B2UWE6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program