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B2UUK7

- GLK_HELPS

UniProt

B2UUK7 - GLK_HELPS

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Protein
Glucokinase
Gene
glk, HPSH_05665
Organism
Helicobacter pylori (strain Shi470)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 176ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPYL512562:GHHZ-1125-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:HPSH_05665
OrganismiHelicobacter pylori (strain Shi470)
Taxonomic identifieri512562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000008831: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336GlucokinaseUniRule annotation
PRO_1000127710Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi512562.HPSH_05665.

Structurei

3D structure databases

ProteinModelPortaliB2UUK7.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiDKAPHSA.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

B2UUK7-1 [UniParc]FASTAAdd to Basket

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MPKTETYPRL LADIGGTNAR FGLEVAPRQI ECIEVLPCKD FESLSDAVRF    50
YLSKCKESLK LHPIYGSFAV ATPIMGDFVQ MTNNHWTFSI ETTRQCLDLK 100
KLLVINDFVA QAYAISAMQE NDLAQIGGIK CEINAPKAIL GPGTGLGVST 150
LIQNSDGSLK VLPGEGGHVS FAPFDDLEIL VWQYARSKFN HVSAERFLSG 200
SGLVLIYEAL SKRKGLEKVA KLSKAELTPQ IISERALNGD YPICRLTLDT 250
FCSMLGTLAA DVALTLGARG GVYLCGGIIP RFIDYFKTSP FRARFETKGR 300
MGAFLASIPV HVVLKKTPGL DGAGIALENY LLHDKI 336
Length:336
Mass (Da):36,668
Last modified:July 1, 2008 - v1
Checksum:i1393DF05E2F4061C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001072 Genomic DNA. Translation: ACD48539.1.
RefSeqiYP_001910569.1. NC_010698.2.

Genome annotation databases

EnsemblBacteriaiACD48539; ACD48539; HPSH_05665.
GeneIDi6297293.
KEGGihps:HPSH_05665.
PATRICi20613611. VBIHelPyl23559_1103.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001072 Genomic DNA. Translation: ACD48539.1 .
RefSeqi YP_001910569.1. NC_010698.2.

3D structure databases

ProteinModelPortali B2UUK7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 512562.HPSH_05665.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD48539 ; ACD48539 ; HPSH_05665 .
GeneIDi 6297293.
KEGGi hps:HPSH_05665.
PATRICi 20613611. VBIHelPyl23559_1103.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi DKAPHSA.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci HPYL512562:GHHZ-1125-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Helicobacter pylori from the remote Amazon: traces of Asian ancestry of the first Americans."
    Kersulyte D., Kalia A., Gilman R.H., Berg D.E.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Shi470.

Entry informationi

Entry nameiGLK_HELPS
AccessioniPrimary (citable) accession number: B2UUK7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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