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B2UUK7 (GLK_HELPS) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:HPSH_05665
OrganismHelicobacter pylori (strain Shi470) [Complete proteome] [HAMAP]
Taxonomic identifier512562 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Glucokinase HAMAP-Rule MF_00524
PRO_1000127710

Regions

Nucleotide binding12 – 176ATP Potential

Sequences

Sequence LengthMass (Da)Tools
B2UUK7 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 1393DF05E2F4061C

FASTA33636,668
        10         20         30         40         50         60 
MPKTETYPRL LADIGGTNAR FGLEVAPRQI ECIEVLPCKD FESLSDAVRF YLSKCKESLK 

        70         80         90        100        110        120 
LHPIYGSFAV ATPIMGDFVQ MTNNHWTFSI ETTRQCLDLK KLLVINDFVA QAYAISAMQE 

       130        140        150        160        170        180 
NDLAQIGGIK CEINAPKAIL GPGTGLGVST LIQNSDGSLK VLPGEGGHVS FAPFDDLEIL 

       190        200        210        220        230        240 
VWQYARSKFN HVSAERFLSG SGLVLIYEAL SKRKGLEKVA KLSKAELTPQ IISERALNGD 

       250        260        270        280        290        300 
YPICRLTLDT FCSMLGTLAA DVALTLGARG GVYLCGGIIP RFIDYFKTSP FRARFETKGR 

       310        320        330 
MGAFLASIPV HVVLKKTPGL DGAGIALENY LLHDKI 

« Hide

References

[1]"Genome sequence of Helicobacter pylori from the remote Amazon: traces of Asian ancestry of the first Americans."
Kersulyte D., Kalia A., Gilman R.H., Berg D.E.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Shi470.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001072 Genomic DNA. Translation: ACD48539.1.
RefSeqYP_001910569.1. NC_010698.2.

3D structure databases

ProteinModelPortalB2UUK7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING512562.HPSH_05665.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD48539; ACD48539; HPSH_05665.
GeneID6297293.
KEGGhps:HPSH_05665.
PATRIC20613611. VBIHelPyl23559_1103.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OMADKAPHSA.
OrthoDBEOG64BQ47.

Enzyme and pathway databases

BioCycHPYL512562:GHHZ-1125-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_HELPS
AccessionPrimary (citable) accession number: B2UUK7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families