Reviewed, UniProtKB/Swiss-Prot B2URN8 (CYSD_AKKM8)

Names and origin

Protein names

Recommended name:
    Sulfate adenylyltransferase subunit 2
    EC=2.7.7.4
Alternative name(s):
    Sulfate adenylate transferase
      Short name=SAT
    ATP-sulfurylase small subunit

Gene names

Name:	cysD
Ordered Locus Names:	Amuc_1299

Organism

Akkermansia muciniphila (strain ATCC BAA-835) [Complete proteome] [HAMAP]

Taxonomic identifier

349741 [NCBI]

Taxonomic lineage

Bacteria › Verrucomicrobia › Verrucomicrobiae › Verrucomicrobiales › Verrucomicrobiaceae › Akkermansia

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of cysD, the smaller subunit, and cysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000116955

Sequences

	Sequence		Length	Mass (Da)
	B2URN8-1 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: FF5394C90EFB563E	FASTA	303	35,310
	10 20 30 40 50 60 MNSIYRLSQL KQLEAESIHI FRDAISQFEN PVLLYSIGKD SSVLVHLAKK AFYPGRLPFK 70 80 90 100 110 120 LLHIDSTFKF REMIEFRDRF VQENDLDLIV HSNQEGISAG VNPFTYGSRK YTDIMKTQAL 130 140 150 160 170 180 IQALTAGKYD AVFGGARRDE EKSRAKERIF SFRDKFNQWD PKNQRPELWN IYNGRINPGE 190 200 210 220 230 240 SVRIFPLSNW TELDIWQYIR LEKIQVVDLY FARPRPIVER DGSLIMADDD RLPLKPGETP 250 260 270 280 290 300 QMRTVRFRTL GCYPLTGAIE STARTVEEIV AEMLETRLSE RSSRIIDHDG DASMEQKKRE GYF

References

[1]

"Complete sequence of Akkermansia muciniphila ATCC BAA-835." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. , Smidt H., Derrien M., Plugge C.M., Zoetendal E.G., de Vos W.M., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001071 Genomic DNA. Translation: ACD05123.1.
RefSeq	YP_001877904.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6275588.
GenomeReviews	Gene locus Amuc_1299 in contig CP001071_GR.
KEGG	amu:Amuc_1299.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SLRVFPL.
Family and domain databases
HAMAP	MF_00064. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_AKKM8

Accession

Primary (citable) accession number: B2URN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	November 3, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)