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B2UQ45 (B2UQ45_AKKM8) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361

EC=2.5.1.54 PIRNR PIRNR001361
Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361
Gene names
Ordered Locus Names:Amuc_0744 EMBL ACD04580.1
OrganismAkkermansia muciniphila (strain ATCC BAA-835) [Complete proteome] [HAMAP] EMBL ACD04580.1
Taxonomic identifier349741 [NCBI]
Taxonomic lineageBacteriaVerrucomicrobiaVerrucomicrobiaeVerrucomicrobialesVerrucomicrobiaceaeAkkermansia

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361

Catalytic activity

Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361

Sequence similarities

Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Sequences

Sequence LengthMass (Da)Tools
B2UQ45 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 7E3738688163E90E

FASTA35538,806
        10         20         30         40         50         60 
MNWFKTDDIR IQDIEPLISP AILIKDYPAT TEIAKMVATT RKNAENIISG HDDRLLVVVG 

        70         80         90        100        110        120 
PCSIHDPQAA VDYASRLKEQ MARFEKDLVI IMRVYFEKPR TTVGWKGLIN DPFMNHTFDI 

       130        140        150        160        170        180 
NRGLHMARGL LLRLGDMGVP AATEFLDTIT PQYIADLITW GAIGARTTES QVHRELASGL 

       190        200        210        220        230        240 
SMPVGFKNGT SGSLQIAVDA IVSSSCPHCF LSVTKQGVSA IVSTTGNKSC HLILRGSSLG 

       250        260        270        280        290        300 
PNFDEDHVKE AEEALQKAGI NNRIMIDCSH GNSCKDYRKQ PAVAANIAEQ ISSGSEQVVA 

       310        320        330        340        350 
VMIESNIVEG AQPLSSDLVY GKSITDQCIG WETTVEVLET LAAAVRKRRA KRQEA 

« Hide

References

[1]"Complete sequence of Akkermansia muciniphila ATCC BAA-835."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. expand/collapse author list , Smidt H., Derrien M., Plugge C.M., Zoetendal E.G., de Vos W.M., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-835 EMBL ACD04580.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001071 Genomic DNA. Translation: ACD04580.1.
RefSeqYP_001877361.1. NC_010655.1.

3D structure databases

ProteinModelPortalB2UQ45.
SMRB2UQ45. Positions 8-349.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349741.Amuc_0744.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD04580; ACD04580; Amuc_0744.
GeneID6275534.
KEGGamu:Amuc_0744.
PATRIC20834180. VBIAkkMuc16855_0843.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0722.
HOGENOMHOG000220501.
KOK01626.
OMAHLIREFP.
OrthoDBEOG63JR9W.
ProtClustDBPRK09261.

Enzyme and pathway databases

BioCycAMUC349741:GHZ7-767-MONOMER.
UniPathwayUPA00053; UER00084.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006219. DHAP_synth_1.
[Graphical view]
PANTHERPTHR21225. PTHR21225. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
PIRSFPIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMsTIGR00034. aroFGH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2UQ45_AKKM8
AccessionPrimary (citable) accession number: B2UQ45
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: November 13, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)