B2UPI5 (B2UPI5_AKKM8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Exo-alpha-sialidase EMBL ACD04462.1
EC=3.2.1.18 EMBL ACD04462.1

Gene names

Ordered Locus Names:

Amuc_0625

Organism

Akkermansia muciniphila (strain ATCC BAA-835) [Complete proteome] [HAMAP] EMBL ACD04462.1

Taxonomic identifier

349741 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chlamydiae/Verrucomicrobia group › Verrucomicrobia › Verrucomicrobiae › Verrucomicrobiales › Verrucomicrobiaceae › Akkermansia › Akkermansia muciniphila

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

Ontologies

Keywords
Domain	Signal EMBL ACD04462.1
Molecular function	Glycosidase EMBL ACD04462.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	exo-alpha-(2->3)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->6)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->8)-sialidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 39	39	Potential EMBL ACD04462.1
	Chain	40 – 419	380	Potential EMBL ACD04462.1		PRO_5000370509

Sequences

	Sequence		Length	Mass (Da)
	B2UPI5 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 6CF910299C76EABA	FASTA	419	45,589
	10 20 30 40 50 60 MTWLLCGRGK WNKVKRMMNS VFKCLMSAVC AVALPAFGQE EKTGFPTDRA VTVFSAGEGN 70 80 90 100 110 120 PYASIRIPAL LSIGKGQLLA FAEGRYKNTD QGENDIIMSV SKNGGKTWSR PRAIAKAHGA 130 140 150 160 170 180 TFNNPCPVYD AKTRTVTVVF QRYPAGVKER QPNIPDGWDD EKCIRNFMIQ SRNGGSSWTK 190 200 210 220 230 240 PQEITKTTKR PSGVDIMASG PNAGTQLKSG AHKGRLVIPM NEGPFGKWVI SCIYSDDGGK 250 260 270 280 290 300 SWKLGQPTAN MKGMVNETSI AETDNGGVVM VARHWGAGNC RRIAWSQDGG ETWGQVEDAP 310 320 330 340 350 360 ELFCDSTQNS LMTYSLSDQP AYGGKSRILF SGPSAGRRIK GQVAMSYDNG KTWPVKKLLG 370 380 390 400 410 EGGFAYSSLA MVEPGIVGVL YEENQEHIKK LKFVPITMEW LTDGEDTGLA PGKKAPVLK

References

[1]

"Complete sequence of Akkermansia muciniphila ATCC BAA-835." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. , Smidt H., Derrien M., Plugge C.M., Zoetendal E.G., de Vos W.M., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-835 EMBL ACD04462.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001071 Genomic DNA. Translation: ACD04462.1.
RefSeq	YP_001877243.1. NC_010655.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	349741.Amuc_0625.
Protein family/group databases
CAZy	GH33. Glycoside Hydrolase Family 33.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACD04462; ACD04462; Amuc_0625.
GeneID	6274199.
KEGG	amu:Amuc_0625.
PATRIC	20833906. VBIAkkMuc16855_0707.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4409.
KO	K01186.
OMA	FDMELRS.
Enzyme and pathway databases
BioCyc	AMUC349741:GHZ7-647-MONOMER.
Family and domain databases
Gene3D	2.120.10.10. 1 hit.
InterPro	IPR026948. Sialidase. IPR026856. Sialidase_fam. IPR011040. Sialidases. [Graphical view]
PANTHER	PTHR10628. PTHR10628. 1 hit. PTHR10628:SF5. PTHR10628:SF5. 1 hit.
SUPFAM	SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2UPI5_AKKM8

Accession

Primary (citable) accession number: B2UPI5

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)