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Protein

Glutamate decarboxylase

Gene

Amuc_0372

Organism
Akkermansia muciniphila (strain ATCC BAA-835 / Muc)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciAMUC349741:G1GBX-415-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Amuc_0372Imported
OrganismiAkkermansia muciniphila (strain ATCC BAA-835 / Muc)Imported
Taxonomic identifieri349741 [NCBI]
Taxonomic lineageiBacteriaVerrucomicrobiaVerrucomicrobiaeVerrucomicrobialesAkkermansiaceaeAkkermansia
Proteomesi
  • UP000001031 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei274N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi349741.Amuc_0372

Structurei

3D structure databases

ProteinModelPortaliB2UN99
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

B2UN99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDPNQKPDT ARAENSIFGS PEADNLLPKD EFPDYAMRAE DAFQLVSDEL
60 70 80 90 100
MLDGNARQNL ATFCQTWDEK QVRMLMNLSI NKNMIDKDEY PQTAAIEMRC
110 120 130 140 150
AAIIANLWNA SQNEKPIGCS TIGSSEACML GGMAALWRWR ARRKAAGKPI
160 170 180 190 200
DKPNLVCGPV QICWHKFCRY WDIEMREIPM VPGKWKMDVD RMLEQIDENT
210 220 230 240 250
IVVVPTFGVT YTGAYELPAE IAKALDDYEN KTGISVDIHV DGASGGFLAP
260 270 280 290 300
FCAPDLVFDF RIPRVKSISA SGHKYGLAPL GVGWVVWRDI SELPEGLIFN
310 320 330 340 350
VNYLGGEIPN FAINFSRPAG QIICQYYDFI RLGKEGYTNI HTQAYEVAKY
360 370 380 390 400
ISDELSKLGP YEFICTGDPE KGIPAVCFFI KDGARANYTL FDLSDKLRTR
410 420 430 440 450
GWQVPAFTLP ANCQDTVVMR VMVRQGFSKD LADLFLEDYK RMLSFFEKHP
460
VSSPMTAEEG TAFHHS
Length:466
Mass (Da):52,458
Last modified:July 1, 2008 - v1
Checksum:i01AAA28F18791379
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001071 Genomic DNA Translation: ACD04211.1
RefSeqiWP_012419426.1, NC_010655.1

Genome annotation databases

EnsemblBacteriaiACD04211; ACD04211; Amuc_0372
GeneIDi34173815
KEGGiamu:Amuc_0372

Similar proteinsi

Entry informationi

Entry nameiB2UN99_AKKM8
AccessioniPrimary (citable) accession number: B2UN99
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 25, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health