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B2UN42

- B2UN42_AKKM8

UniProt

B2UN42 - B2UN42_AKKM8

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Protein
Submitted name: Exo-alpha-sialidase
Gene
Amuc_1835
Organism
Akkermansia muciniphila (strain ATCC BAA-835)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    GlycosidaseImported, Hydrolase

    Enzyme and pathway databases

    BioCyciAMUC349741:GHZ7-1890-MONOMER.

    Protein family/group databases

    CAZyiGH33. Glycoside Hydrolase Family 33.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Exo-alpha-sialidaseImported (EC:3.2.1.18Imported)
    Gene namesi
    Ordered Locus Names:Amuc_1835Imported
    OrganismiAkkermansia muciniphila (strain ATCC BAA-835)Imported
    Taxonomic identifieri349741 [NCBI]
    Taxonomic lineageiBacteriaVerrucomicrobiaVerrucomicrobiaeVerrucomicrobialesVerrucomicrobiaceaeAkkermansia
    ProteomesiUP000001031: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919 PredictedImported
    Add
    BLAST
    Chaini20 – 674655 PredictedImported
    PRO_5000370394Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi349741.Amuc_1835.

    Family & Domainsi

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    eggNOGiCOG4409.
    HOGENOMiHOG000252336.
    KOiK01186.
    OrthoDBiEOG67DPK3.

    Family and domain databases

    Gene3Di2.120.10.10. 1 hit.
    InterProiIPR026856. Sialidase_fam.
    IPR029456. Sialidase_N.
    IPR011040. Sialidases.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PfamiPF14873. BNR_assoc_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF50939. SSF50939. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    B2UN42-1 [UniParc]FASTAAdd to Basket

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    MGLGLLCALG LSIPSVLGKE SFEQARRGKF TTLSTKYGLM SCRNGVAEIG    50
    GGGKSGEASL RMFGGQDAEL KLDLKDTPSR EVRLSAWAER WTGQAPFEFS 100
    IVAIGPNGEK KIYDGKDIRT GGFHTRIEAS VPAGTRSLVF RLTSPENKGM 150
    KLDDLFLVPC IPMKVNPQVE MASSAYPVMV RIPCSPVLSL NVRTDGCLNP 200
    QFLTAVNLDF TGTTKLSDIE SVAVIRGEEA PIIHHGEEPF PKDSSQVLGT 250
    VKLAGSARPQ ISVKGKMELE PGDNYLWACV TMKEGASLDG RVVVRPASVV 300
    AGNKPVRVAN AAPVAQRIGV AVVRHGDFKS KFYRIPGLAR SRKGTLLAVY 350
    DIRYNHSGDL PANIDVGVSR STDGGRTWSD VKIAIDDSKI DPSLGATRGV 400
    GDPAILVDEK TGRIWVAAIW SHRHSIWGSK SGDNSPEACG QLVLAYSDDD 450
    GLTWSSPINI TEQTKNKDWR ILFNGPGNGI CMKDGTLVFA AQYWDGKGVP 500
    WSTIVYSKDR GKTWHCGTGV NQQTTEAQVI ELEDGSVMIN ARCNWGGSRI 550
    VGVTKDLGQT WEKHPTNRTA QLKEPVCQGS LLAVDGVPGA GRVVLFSNPN 600
    TTSGRSHMTL KASTNDAGSW PEDKWLLYDA RKGWGYSCLA PVDKNHVGVL 650
    YESQGALNFL KIPYKDVLNA KNAR 674
    Length:674
    Mass (Da):72,840
    Last modified:July 1, 2008 - v1
    Checksum:i6ECC9CBD11BDF1A9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001071 Genomic DNA. Translation: ACD05653.1.
    RefSeqiWP_012420867.1. NC_010655.1.
    YP_001878434.1. NC_010655.1.

    Genome annotation databases

    EnsemblBacteriaiACD05653; ACD05653; Amuc_1835.
    GeneIDi6275505.
    KEGGiamu:Amuc_1835.
    PATRICi20836722. VBIAkkMuc16855_2085.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001071 Genomic DNA. Translation: ACD05653.1 .
    RefSeqi WP_012420867.1. NC_010655.1.
    YP_001878434.1. NC_010655.1.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 349741.Amuc_1835.

    Protein family/group databases

    CAZyi GH33. Glycoside Hydrolase Family 33.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACD05653 ; ACD05653 ; Amuc_1835 .
    GeneIDi 6275505.
    KEGGi amu:Amuc_1835.
    PATRICi 20836722. VBIAkkMuc16855_2085.

    Phylogenomic databases

    eggNOGi COG4409.
    HOGENOMi HOG000252336.
    KOi K01186.
    OrthoDBi EOG67DPK3.

    Enzyme and pathway databases

    BioCyci AMUC349741:GHZ7-1890-MONOMER.

    Family and domain databases

    Gene3Di 2.120.10.10. 1 hit.
    InterProi IPR026856. Sialidase_fam.
    IPR029456. Sialidase_N.
    IPR011040. Sialidases.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    Pfami PF14873. BNR_assoc_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50939. SSF50939. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Akkermansia muciniphila ATCC BAA-835."
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N.
      , Smidt H., Derrien M., Plugge C.M., Zoetendal E.G., de Vos W.M., Richardson P.
      Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-835Imported.

    Entry informationi

    Entry nameiB2UN42_AKKM8
    AccessioniPrimary (citable) accession number: B2UN42
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 2008
    Last sequence update: July 1, 2008
    Last modified: September 3, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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