B2UN42 (B2UN42_AKKM8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Exo-alpha-sialidase EMBL ACD05653.1
EC=3.2.1.18 EMBL ACD05653.1

Gene names

Ordered Locus Names:

Amuc_1835

Organism

Akkermansia muciniphila (strain ATCC BAA-835) [Complete proteome] [HAMAP] EMBL ACD05653.1

Taxonomic identifier

349741 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chlamydiae/Verrucomicrobia group › Verrucomicrobia › Verrucomicrobiae › Verrucomicrobiales › Verrucomicrobiaceae › Akkermansia › Akkermansia muciniphila

Protein attributes

Sequence length	674 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

Ontologies

Keywords
Domain	Signal EMBL ACD05653.1
Molecular function	Glycosidase EMBL ACD05653.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	exo-alpha-(2->3)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->6)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->8)-sialidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential EMBL ACD05653.1
	Chain	20 – 674	655	Potential EMBL ACD05653.1		PRO_5000370394

Sequences

	Sequence		Length	Mass (Da)
	B2UN42 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 6ECC9CBD11BDF1A9	FASTA	674	72,840
	10 20 30 40 50 60 MGLGLLCALG LSIPSVLGKE SFEQARRGKF TTLSTKYGLM SCRNGVAEIG GGGKSGEASL 70 80 90 100 110 120 RMFGGQDAEL KLDLKDTPSR EVRLSAWAER WTGQAPFEFS IVAIGPNGEK KIYDGKDIRT 130 140 150 160 170 180 GGFHTRIEAS VPAGTRSLVF RLTSPENKGM KLDDLFLVPC IPMKVNPQVE MASSAYPVMV 190 200 210 220 230 240 RIPCSPVLSL NVRTDGCLNP QFLTAVNLDF TGTTKLSDIE SVAVIRGEEA PIIHHGEEPF 250 260 270 280 290 300 PKDSSQVLGT VKLAGSARPQ ISVKGKMELE PGDNYLWACV TMKEGASLDG RVVVRPASVV 310 320 330 340 350 360 AGNKPVRVAN AAPVAQRIGV AVVRHGDFKS KFYRIPGLAR SRKGTLLAVY DIRYNHSGDL 370 380 390 400 410 420 PANIDVGVSR STDGGRTWSD VKIAIDDSKI DPSLGATRGV GDPAILVDEK TGRIWVAAIW 430 440 450 460 470 480 SHRHSIWGSK SGDNSPEACG QLVLAYSDDD GLTWSSPINI TEQTKNKDWR ILFNGPGNGI 490 500 510 520 530 540 CMKDGTLVFA AQYWDGKGVP WSTIVYSKDR GKTWHCGTGV NQQTTEAQVI ELEDGSVMIN 550 560 570 580 590 600 ARCNWGGSRI VGVTKDLGQT WEKHPTNRTA QLKEPVCQGS LLAVDGVPGA GRVVLFSNPN 610 620 630 640 650 660 TTSGRSHMTL KASTNDAGSW PEDKWLLYDA RKGWGYSCLA PVDKNHVGVL YESQGALNFL 670 KIPYKDVLNA KNAR

References

[1]

"Complete sequence of Akkermansia muciniphila ATCC BAA-835." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. , Smidt H., Derrien M., Plugge C.M., Zoetendal E.G., de Vos W.M., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-835 EMBL ACD05653.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001071 Genomic DNA. Translation: ACD05653.1.
RefSeq	YP_001878434.1. NC_010655.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	349741.Amuc_1835.
Protein family/group databases
CAZy	GH33. Glycoside Hydrolase Family 33.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACD05653; ACD05653; Amuc_1835.
GeneID	6275505.
KEGG	amu:Amuc_1835.
PATRIC	20836722. VBIAkkMuc16855_2085.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4409.
HOGENOM	HOG000252336.
KO	K01186.
OMA	HTRIEAS.
Enzyme and pathway databases
BioCyc	AMUC349741:GHZ7-1890-MONOMER.
Family and domain databases
Gene3D	2.120.10.10. 1 hit.
InterPro	IPR026948. Sialidase. IPR026856. Sialidase_fam. IPR011040. Sialidases. [Graphical view]
PANTHER	PTHR10628. PTHR10628. 1 hit. PTHR10628:SF5. PTHR10628:SF5. 1 hit.
SUPFAM	SSF50939. Sialidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2UN42_AKKM8

Accession

Primary (citable) accession number: B2UN42

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)