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B2UN39 (B2UN39_AKKM8) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
L-fucose isomerase HAMAP-Rule MF_01254
EC=5.3.1.25 HAMAP-Rule MF_01254
Alternative name(s):
6-deoxy-L-galactose isomerase HAMAP-Rule MF_01254
FucIase HAMAP-Rule MF_01254
Gene names
Name:fucI HAMAP-Rule MF_01254
Ordered Locus Names:Amuc_1832
OrganismAkkermansia muciniphila (strain ATCC BAA-835) [Complete proteome] [HAMAP] EMBL ACD05650.1
Taxonomic identifier349741 [NCBI]
Taxonomic lineageBacteria › Verrucomicrobia › Verrucomicrobiae › Verrucomicrobiales › Verrucomicrobiaceae › Akkermansia ›

Protein attributes

Sequence length592 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts the aldose L-fucose into the corresponding ketose L-fuculose By similarity. HAMAP-Rule MF_01254

Catalytic activity

L-fucose = L-fuculose. HAMAP-Rule MF_01254 SAAS SAAS012888

Cofactor

Manganese By similarity. HAMAP-Rule MF_01254 SAAS SAAS012888

Pathway

Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 1/3. HAMAP-Rule MF_01254 SAAS SAAS012888

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01254.

Sequence similarities

Belongs to the L-fucose isomerase family. HAMAP-Rule MF_01254

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site3361Proton acceptor By similarity HAMAP-Rule MF_01254
Active site3601Proton acceptor By similarity HAMAP-Rule MF_01254
Metal binding3361Manganese By similarity HAMAP-Rule MF_01254
Metal binding3601Manganese By similarity HAMAP-Rule MF_01254
Metal binding5271Manganese By similarity HAMAP-Rule MF_01254

Sequences

Sequence LengthMass (Da)Tools
B2UN39 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 2A693E6BF9C66336

FASTA59264,696
        10         20         30         40         50         60 
MKTALPTIGI RPTIDGRRLG VRESLEDQTM NMAKAAAALI EANIRHASGE PVKCVIADTC 

        70         80         90        100        110        120 
IGGPAEAAAC ADKFKANNVG VSLAVTPCWC YGSETFDMDP FTPKAIWGFN GTERPGAVYL 

       130        140        150        160        170        180 
AAALAGLNQK GFPAFSIYGK DVQDATDTSI PEDVAEKILR FCRAGLAVAT LRGKGYLSIG 

       190        200        210        220        230        240 
GCSMGIAGSI VDQSFWENYL GIRVQAVDMT EVRRRMDQKI YDEAEFDLAM QWADSVFKFA 

       250        260        270        280        290        300 
EDKNRPDLKL DEAGRRKTFR ESVLMAMIFR DMMQGNPKLK KIDREEESLG YQAIAGGFQG 

       310        320        330        340        350        360 
QRHWTDFYPN GDIAETLLNS TFDWNGPRAP LPFATENDSL NGACLLFGYL LTGQANVFAD 

       370        380        390        400        410        420 
VRTYWSPEAV KRVTGYTLEG HAKDGIIHLI NSGSAALDGC MACTGKDGQP VMKKHWDVTP 

       430        440        450        460        470        480 
DDAKTMMEQA VWCPANREYF RGGGYSVHYV TRGGAPVTMM RLNIVKGLGP VLIVAEGWSV 

       490        500        510        520        530        540 
DLPAEVHKTL DERTDPGWPT TWFAPRLTGK GAFTDVYSVM ANMGANHGAF TYGHIGADIL 

       550        560        570        580        590 
TLASMLRIPV YAHNIPDDQI YRPSAWGLHG TADPEGADFR ACANYGPLYG KY

« Hide

References

[1]"Complete sequence of Akkermansia muciniphila ATCC BAA-835."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N. expand/collapse author list , Smidt H., Derrien M., Plugge C.M., Zoetendal E.G., de Vos W.M., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-835 EMBL ACD05650.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001071 Genomic DNA. Translation: ACD05650.1.
RefSeqYP_001878431.1. NC_010655.1.

3D structure databases

ProteinModelPortalB2UN39.
SMRB2UN39. Positions 2-591.
ModBaseSearch...

Protein-protein interaction databases

STRING349741.Amuc_1832.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD05650; ACD05650; Amuc_1832.
GeneID6275647.
KEGGamu:Amuc_1832.
PATRIC20836716. VBIAkkMuc16855_2082.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2407.
HOGENOMHOG000249674.
KOK01818.
OMAKIGIRPT.
ProtClustDBPRK10991.

Enzyme and pathway databases

BioCycAMUC349741:GHZ7-1887-MONOMER.
UniPathwayUPA00563; UER00624.

Family and domain databases

Gene3D3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPMF_01254. Fucose_iso.
InterProIPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view]
PfamPF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view]
SUPFAMSSF50443. Fuc_isomerase_C. 1 hit.
SSF53743. Fuc_isomerase_N. 1 hit.
TIGRFAMsTIGR01089. fucI. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2UN39_AKKM8
AccessionPrimary (citable) accession number: B2UN39
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info