B2UGP7 (GLMM_RALPJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Rpic_2027

Organism

Ralstonia pickettii (strain 12J) [Complete proteome] [HAMAP]

Taxonomic identifier

402626 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia › Burkholderia pickettii

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP-Rule MF_01554		PRO_1000201128
Sites
	Active site	107	1	Phosphoserine intermediate By similarity
	Metal binding	107	1	Magnesium; via phosphate group By similarity
	Metal binding	246	1	Magnesium By similarity
	Metal binding	248	1	Magnesium By similarity
	Metal binding	250	1	Magnesium By similarity
Amino acid modifications
	Modified residue	107	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B2UGP7 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 566F67B2EBF737D5	FASTA	447	47,787
	10 20 30 40 50 60 MSRKYFGTDG IRGRVGESPI TPDFVLRLGY AAGRVLAHGG EAHGHGRPTV LIGKDTRLSG 70 80 90 100 110 120 YMLEAALEAG FTAAGVDVLM SGPLPTPGVA YLTRALRLSA GVVISASHNP YYDNGIKFFS 130 140 150 160 170 180 ATGDKLPDET ELQIEAELEK PMAYAASDAL GRARRIEDAA GRYIEFCKST FPSDLNLFGM 190 200 210 220 230 240 KVVLDSAHGA AYHIAPHVFH ELGADVVSIG NQPNGRNIND GYGATAPGKL VEATREHGAD 250 260 270 280 290 300 IGLAFDGDAD RLQVVDRNGR LYNGDELLYV MVQARRAAGQ TVPGAVGTLM TNLAVELALK 310 320 330 340 350 360 AQGVEFVRAK VGDRYVLEEL KKNGWLLGGE GSGHLLCLDK HSTGDGIISA LQVLAALRRS 370 380 390 400 410 420 GQTLDEMLDG VRLFPQKLIN VRVEKGFDWK SHAGLQAALK TSEAELDGKG RVLIRPSGTE 430 440 PVVRVMVEAQ DAELANQHAE RLAATLQ

References

[1]

"Complete sequence of chromosome 1 of Ralstonia pickettii 12J." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Marsh T., Richardson P. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12J.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001068 Genomic DNA. Translation: ACD27161.1.
RefSeq	YP_001899593.1. NC_010682.1.
3D structure databases
ProteinModelPortal	B2UGP7.
ModBase	Search...
Protein-protein interaction databases
STRING	402626.Rpic_2027.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACD27161; ACD27161; Rpic_2027.
GeneID	6287751.
KEGG	rpi:Rpic_2027.
PATRIC	20254868. VBIRalPic63053_3178.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000268678.
KO	K03431.
OMA	TLMSNMS.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	RPIC402626:GH94-2145-MONOMER.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
HAMAP	MF_01554_B. GlmM_B.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_RALPJ

Accession

Primary (citable) accession number: B2UGP7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	July 1, 2008
Last modified:	May 1, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program