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Protein

Aminomethyltransferase

Gene

gcvT

Organism
Ralstonia pickettii (strain 12J)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Alternative name(s):
Glycine cleavage system T proteinUniRule annotation
Gene namesi
Name:gcvTUniRule annotation
Ordered Locus Names:Rpic_3487
OrganismiRalstonia pickettii (strain 12J)
Taxonomic identifieri402626 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
Proteomesi
  • UP000002566 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001141081 – 375AminomethyltransferaseAdd BLAST375

Proteomic databases

PRIDEiB2UG80

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi402626.Rpic_3487

Structurei

3D structure databases

ProteinModelPortaliB2UG80
SMRiB2UG80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D43 Bacteria
COG0404 LUCA
HOGENOMiHOG000239381
KOiK00605
OMAiMPVQYPA

Family and domain databases

Gene3Di3.30.1360.120, 2 hits
HAMAPiMF_00259 GcvT, 1 hit
InterProiView protein in InterPro
IPR006223 GCS_T
IPR022903 GCS_T_bac
IPR028896 GCST/YgfZ/DmdA
IPR013977 GCV_T_C
IPR006222 GCV_T_N
IPR029043 GcvT/YgfZ_C
IPR027266 TrmE/GcvT_dom1
PfamiView protein in Pfam
PF01571 GCV_T, 1 hit
PF08669 GCV_T_C, 1 hit
PIRSFiPIRSF006487 GcvT, 1 hit
SUPFAMiSSF101790 SSF101790, 1 hit
TIGRFAMsiTIGR00528 gcvT, 1 hit

Sequencei

Sequence statusi: Complete.

B2UG80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLQHTPLNA IHRSLGARMV DFGGWDMPVN YGSQIEEHHA VRQDAGVFDV
60 70 80 90 100
SHMCVVDLTG ARVRDFLRGL LANNVDKLQT PGKALYSCML NPKGGVIDDL
110 120 130 140 150
IVYFFREDWF RLVVNAGTAP TDLEWIVAQN AAAGTDVTIT PRRSDNNAGA
160 170 180 190 200
EPLGILAVQG PNARAKTYAA LPGSQAVGDA LKPFNAGFVT VENVGEIMVA
210 220 230 240 250
RTGYTGEDGF ELVVPAAQIA GVWERLLQAG VRPAGLGARD TLRLEAGMNL
260 270 280 290 300
YGQDMDEHVS PLDAGLAWTV DLQSERDFTG KAALQAGGQR EQFVGLILRD
310 320 330 340 350
KGGVLRAHQK VITAAGDGEI TSGTFSPSLS LSIALARLPK EVPVGTDVQV
360 370
EIRDRKLTAT VVKLPFVRNG KALVS
Length:375
Mass (Da):40,148
Last modified:July 1, 2008 - v1
Checksum:i6E8CAE7C9F89D7CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001068 Genomic DNA Translation: ACD28607.1
RefSeqiWP_004628681.1, NC_010682.1

Genome annotation databases

EnsemblBacteriaiACD28607; ACD28607; Rpic_3487
GeneIDi6286303
KEGGirpi:Rpic_3487

Similar proteinsi

Entry informationi

Entry nameiGCST_RALPJ
AccessioniPrimary (citable) accession number: B2UG80
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: June 20, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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