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B2UG80

- GCST_RALPJ

UniProt

B2UG80 - GCST_RALPJ

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Protein
Aminomethyltransferase
Gene
gcvT, Rpic_3487
Organism
Ralstonia pickettii (strain 12J)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine By similarity.UniRule annotation

Catalytic activityi

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

  1. aminomethyltransferase activity Source: UniProtKB-EC
  2. transaminase activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. glycine catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciRPIC402626:GH94-3544-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aminomethyltransferase (EC:2.1.2.10)
Alternative name(s):
Glycine cleavage system T protein
Gene namesi
Name:gcvT
Ordered Locus Names:Rpic_3487
OrganismiRalstonia pickettii (strain 12J)
Taxonomic identifieri402626 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
ProteomesiUP000002566: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 375375AminomethyltransferaseUniRule annotation
PRO_1000114108Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Protein-protein interaction databases

STRINGi402626.Rpic_3487.

Structurei

3D structure databases

ProteinModelPortaliB2UG80.
SMRiB2UG80. Positions 5-373.

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.

Phylogenomic databases

eggNOGiCOG0404.
HOGENOMiHOG000239381.
KOiK00605.
OMAiPFFGVQS.
OrthoDBiEOG6T1WS5.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
HAMAPiMF_00259. GcvT.
InterProiIPR006223. GCS_T.
IPR022903. GCS_T_bac.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.

Sequencei

Sequence statusi: Complete.

B2UG80-1 [UniParc]FASTAAdd to Basket

« Hide

MTLQHTPLNA IHRSLGARMV DFGGWDMPVN YGSQIEEHHA VRQDAGVFDV    50
SHMCVVDLTG ARVRDFLRGL LANNVDKLQT PGKALYSCML NPKGGVIDDL 100
IVYFFREDWF RLVVNAGTAP TDLEWIVAQN AAAGTDVTIT PRRSDNNAGA 150
EPLGILAVQG PNARAKTYAA LPGSQAVGDA LKPFNAGFVT VENVGEIMVA 200
RTGYTGEDGF ELVVPAAQIA GVWERLLQAG VRPAGLGARD TLRLEAGMNL 250
YGQDMDEHVS PLDAGLAWTV DLQSERDFTG KAALQAGGQR EQFVGLILRD 300
KGGVLRAHQK VITAAGDGEI TSGTFSPSLS LSIALARLPK EVPVGTDVQV 350
EIRDRKLTAT VVKLPFVRNG KALVS 375
Length:375
Mass (Da):40,148
Last modified:July 1, 2008 - v1
Checksum:i6E8CAE7C9F89D7CA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001068 Genomic DNA. Translation: ACD28607.1.
RefSeqiYP_001901039.1. NC_010682.1.

Genome annotation databases

EnsemblBacteriaiACD28607; ACD28607; Rpic_3487.
GeneIDi6286303.
KEGGirpi:Rpic_3487.
PATRICi20257813. VBIRalPic63053_4621.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001068 Genomic DNA. Translation: ACD28607.1 .
RefSeqi YP_001901039.1. NC_010682.1.

3D structure databases

ProteinModelPortali B2UG80.
SMRi B2UG80. Positions 5-373.
ModBasei Search...

Protein-protein interaction databases

STRINGi 402626.Rpic_3487.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD28607 ; ACD28607 ; Rpic_3487 .
GeneIDi 6286303.
KEGGi rpi:Rpic_3487.
PATRICi 20257813. VBIRalPic63053_4621.

Phylogenomic databases

eggNOGi COG0404.
HOGENOMi HOG000239381.
KOi K00605.
OMAi PFFGVQS.
OrthoDBi EOG6T1WS5.

Enzyme and pathway databases

BioCyci RPIC402626:GH94-3544-MONOMER.

Family and domain databases

Gene3Di 2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
HAMAPi MF_00259. GcvT.
InterProi IPR006223. GCS_T.
IPR022903. GCS_T_bac.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view ]
PANTHERi PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfami PF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF006487. GcvT. 1 hit.
SUPFAMi SSF101790. SSF101790. 1 hit.
TIGRFAMsi TIGR00528. gcvT. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Ralstonia pickettii 12J."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Mikhailova N., Marsh T., Richardson P.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 12J.

Entry informationi

Entry nameiGCST_RALPJ
AccessioniPrimary (citable) accession number: B2UG80
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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