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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Ralstonia pickettii (strain 12J)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei210 – 2101UniRule annotation
Active sitei650 – 6501UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciRPIC402626:GH94-2609-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Rpic_2572Imported
OrganismiRalstonia pickettii (strain 12J)Imported
Taxonomic identifieri402626 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
ProteomesiUP000002566 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi402626.Rpic_2572.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2UA06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQPAARRAS SRATTARKAS AAPAKTSKAT KAIKAAKPAA KPVAKANGAD
60 70 80 90 100
EANGASLGPT SRRSSGSAAA KDQPLKEDIR FLGRLLGDVL REQEGGAAFE
110 120 130 140 150
TVETIRQTAV RFRRDGDRQA EQELDRLLKA LSREQTNSVV RAFSYFSHLA
160 170 180 190 200
NIAEDQHHNR RRRVHALAGS PPQPGSMMRA LLSVADEGVS GETLRRFFDA
210 220 230 240 250
ALIVPVLTAH PTEVQRKSIL DAQREIARLL AERDTPLTTR ERERNTTLLR
260 270 280 290 300
AHVTKLWQTR MLRTTRLMVA DEIENALSYY QTTFLREIPA LYRELEEDVA
310 320 330 340 350
AVFPRRGARG EPTPLAPFFQ MGSWIGGDRD GNPFVTAETL RYAARKQASV
360 370 380 390 400
ILAWYLEEIH ALGAELSMST SQVDVSAELL ALAEQSPDRS EHRSDEPYRR
410 420 430 440 450
ALIGVYARLA ATCRELTGED AGRHAVGPAP AYTSAEELRA DIQIVTDSLA
460 470 480 490 500
AHHGEALADA RLASLARAID VFGFHLSSID LRQVSDVHEA TVAELLKVAG
510 520 530 540 550
VEGAYAALSE ADKRTLLLRE LQQPRLLTLP FHAYSEQTTQ EIDIFRAARE
560 570 580 590 600
VRARYGNRIV RNYIISHTET LSDLLEVMLL QKEAGMFRAN ANGAGVGLDV
610 620 630 640 650
MVIPLFETIE DLRNASQIMG DLLALPGFDA VLAAQGNEQE VMLGYSDSNK
660 670 680 690 700
DGGFLTSNWE LYKAELALVE LFERKGVRLR LFHGRGGTVG RGGGPTYQAI
710 720 730 740 750
LSQPPGTVNG QIRLTEQGEI ISSKFANPEI GRRNLETIVA ATLEATLLPT
760 770 780 790 800
RNRPKGLEEF EAAMQALSDN AFAAYRNLVY ETPGFKDYFF ATTPITEIAD
810 820 830 840 850
LNLGSRPASR KLMDKKHRRI EDLRAIPWGF SWGQCRLLLP GWFGFGSAVQ
860 870 880 890 900
RWLDDAGNAK ARAARLTTLK RMHKQWPFFA NLLSNMDMVL SKADLNVASR
910 920 930 940 950
YAQLCDDRKL RNAVFSRISA EFALTEQMLA AITGQSERLA DNPLLARSIK
960 970 980 990 1000
NRFPYLDPLN HLQVELLKRF RSGKAGSDDA RVRRGIHLSI NGIAAGLRNS

G
Length:1,001
Mass (Da):110,583
Last modified:July 1, 2008 - v1
Checksum:i35BCCA2994AF6E02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001068 Genomic DNA. Translation: ACD27700.1.
RefSeqiWP_004636385.1. NC_010682.1.
YP_001900132.1. NC_010682.1.

Genome annotation databases

EnsemblBacteriaiACD27700; ACD27700; Rpic_2572.
GeneIDi6288587.
KEGGirpi:Rpic_2572.
PATRICi20255938. VBIRalPic63053_3703.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001068 Genomic DNA. Translation: ACD27700.1.
RefSeqiWP_004636385.1. NC_010682.1.
YP_001900132.1. NC_010682.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi402626.Rpic_2572.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACD27700; ACD27700; Rpic_2572.
GeneIDi6288587.
KEGGirpi:Rpic_2572.
PATRICi20255938. VBIRalPic63053_3703.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciRPIC402626:GH94-2609-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Ralstonia pickettii 12J."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Mikhailova N., Marsh T., Richardson P.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 12JImported.

Entry informationi

Entry nameiB2UA06_RALPJ
AccessioniPrimary (citable) accession number: B2UA06
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: May 27, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.