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B2U8V2 (PNCB_RALPJ) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Rpic_0896
OrganismRalstonia pickettii (strain 12J) [Complete proteome] [HAMAP]
Taxonomic identifier402626 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 389389Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000129479

Sequences

Sequence LengthMass (Da)Tools
B2U8V2 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: DAD25AA8D17CDEDF

FASTA38944,841
        10         20         30         40         50         60 
MIIRSLLDTD LYKFTMMQVV LHHFPGAHVE YRFKCRNAGV DLVPFIEEIR AEIRHLCTLR 

        70         80         90        100        110        120 
FTDTELDYLR GMRFIKSDFV DFLGLFHLNE KYIDVRPAPS NDGQIEIVIA GPWLHTIMFE 

       130        140        150        160        170        180 
VPVLAIVNEV FFSRTQTHPQ WEEGKRRLTD KLASLKRPGL EDCRIADYGT RRRFSHTWHE 

       190        200        210        220        230        240 
HVLLETHAQL GAQYAGTSNV YFAMKHGMTP LGTMAHEYLQ ACQALGPRLR DSQTFALETW 

       250        260        270        280        290        300 
AKEYRGDLGI ALSDTYGFDA FLRDFDMFFC KLFDGVRHDS GDPFEWGERM LKHYDDMRAE 

       310        320        330        340        350        360 
PKSKALIFSD SLDMPKVIGL YERFHGRCKL AFGVGTNLTN DLGYTPLQIV IKIVRCNGQP 

       370        380 
VAKLSDAPEK TMCDDPAYLT YLKQVFGVQ 

« Hide

References

[1]"Complete sequence of chromosome 1 of Ralstonia pickettii 12J."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Marsh T., Richardson P.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 12J.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001068 Genomic DNA. Translation: ACD26046.1.
RefSeqYP_001898478.1. NC_010682.1.

3D structure databases

ProteinModelPortalB2U8V2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING402626.Rpic_0896.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACD26046; ACD26046; Rpic_0896.
GeneID6287448.
KEGGrpi:Rpic_0896.
PATRIC20252664. VBIRalPic63053_2096.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycRPIC402626:GH94-902-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_RALPJ
AccessionPrimary (citable) accession number: B2U8V2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 1, 2008
Last modified: March 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways