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Protein

Mannonate dehydratase

Gene

uxuA

Organism
Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the dehydration of D-mannonate.UniRule annotation

Catalytic activityi

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O.UniRule annotation

Cofactori

Fe2+UniRule annotation, Mn2+UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandIron, Manganese

Enzyme and pathway databases

UniPathwayiUPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Mannonate dehydrataseUniRule annotation (EC:4.2.1.8UniRule annotation)
Alternative name(s):
D-mannonate hydro-lyaseUniRule annotation
Gene namesi
Name:uxuAUniRule annotation
Ordered Locus Names:SbBS512_E4792
OrganismiShigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Taxonomic identifieri344609 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000001030 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000942251 – 394Mannonate dehydrataseAdd BLAST394

Proteomic databases

PRIDEiB2TYW4

Structurei

3D structure databases

ProteinModelPortaliB2TYW4
SMRiB2TYW4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannonate dehydratase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000195381
KOiK01686
OMAiIPNGQVW

Family and domain databases

HAMAPiMF_00106 UxuA, 1 hit
InterProiView protein in InterPro
IPR004628 Man_deHydtase
IPR036237 Xyl_isomerase-like_sf
PANTHERiPTHR30387 PTHR30387, 1 hit
PfamiView protein in Pfam
PF03786 UxuA, 1 hit
PIRSFiPIRSF016049 Man_dehyd, 1 hit
SUPFAMiSSF51658 SSF51658, 2 hits
TIGRFAMsiTIGR00695 uxuA, 1 hit

Sequencei

Sequence statusi: Complete.

B2TYW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQTWRWYGP NDLVSLADVR QAGATGVVTA LHHIPNGEVW SVEEILKRKA
60 70 80 90 100
IVEDAGLVWS VVESIPIHED IKTHTGNYEQ WIANYQQTLR NLAQCGIRTV
110 120 130 140 150
CYNFMPVLDW TRTDLEYVLP DGSKALRFDQ IEFAAFEMHI LKRPGAEADY
160 170 180 190 200
TEEEIAQAAE RFATMSDEDK ARLTRNIIAG LPGAEEGYTL DQFRKHLELY
210 220 230 240 250
KDIDKAKLRE NFAVFLKAII PVAEEVGVRM AVHPDDPPRP ILGLPRIVST
260 270 280 290 300
IEDMQWMVDT VNSMANGFTM CTGSYGVRAD NDLVDMIKQF GPRIYFTHLR
310 320 330 340 350
STMREDNPKT FHEAAHLNSD VDMYEVVKAI VEEEHRRKAE GKEDLIPMRP
360 370 380 390
DHGHQMLDDL KKKTNPGYSA IGRLKGLAEV RGVELAIQRA FFSR
Length:394
Mass (Da):44,884
Last modified:July 1, 2008 - v1
Checksum:iE89B520744C4F7DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001063 Genomic DNA Translation: ACD07065.1

Genome annotation databases

EnsemblBacteriaiACD07065; ACD07065; SbBS512_E4792
KEGGisbc:SbBS512_E4792

Similar proteinsi

Entry informationi

Entry nameiUXUA_SHIB3
AccessioniPrimary (citable) accession number: B2TYW4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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