B2TW97 (B2TW97_SHIB3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tetrahydrofolate synthase/dihydrofolate synthase EMBL ACD06395.1
EC=6.3.2.12 EMBL ACD06395.1
EC=6.3.2.17 EMBL ACD06395.1

Gene names

Name:	folC EMBL ACD06395.1
Ordered Locus Names:	SbBS512_E2693 EMBL ACD06395.1

Organism

Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) [Complete proteome] [HAMAP] EMBL ACD06395.1

Taxonomic identifier

344609 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella › Shigella boydii

Protein attributes

Sequence length	422 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS018109 Nucleotide-binding
Molecular function	Ligase EMBL ACD06395.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dihydrofolate biosynthetic process Inferred from electronic annotation. Source: GOC tetrahydrofolylpolyglutamate biosynthetic process Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dihydrofolate synthase activity Inferred from electronic annotation. Source: EC tetrahydrofolylpolyglutamate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2TW97 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: C4BDD5F7ED364FC2	FASTA	422	45,363
	10 20 30 40 50 60 MIIKRTPQAA SPLASWLSYL ENLHSKTIDL GLERVSQVAA RLGVLKPAPF VFTVAGTNGK 70 80 90 100 110 120 GTTCRTLESI LMAAGYKVGV YSSPHLVRYT ERVRVQGQEL PESAHTASFA EIESARGDIS 130 140 150 160 170 180 LTYFEYGTLS ALWLFKQAQL DVVILEVGLG GRLDATNIVD ADVAVVTSIA LDHTDWLGPD 190 200 210 220 230 240 RESIGREKAG IFRSAKPAIV GEPEMPSTIA DVAQEKGALL QRRGVEWNYS VTDHDWAFSD 250 260 270 280 290 300 AHGTLENLPL PLVPQPNAAT ALAALRASGL EVSENAIRDG IASAILPGRF QIVSESPRVI 310 320 330 340 350 360 FDVAHNPHAA EYLTGRMKAL PKNGRVLAVI GMLHDKDIAG TLAWLKSVVD DWYCAPLEGP 370 380 390 400 410 420 RGATAEQLLE HLGNGKSFDS VAQAWDAAMA DAKAEDTVLV CGSFHTVAHV MEVIDARRSG GK

References

[1]

"Complete sequence of Shigella boydii serotype 18 strain BS512." Rasko D.A., Rosovitz M., Maurelli A.T., Myers G., Seshadri R., Cer R., Jiang L., Ravel J., Sebastian Y. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 3083-94 / BS512.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001063 Genomic DNA. Translation: ACD06395.1.
RefSeq	YP_001881137.1. NC_010658.1.
3D structure databases
ProteinModelPortal	B2TW97.
SMR	B2TW97. Positions 6-419.
ModBase	Search...
Protein-protein interaction databases
STRING	344609.SbBS512_E2693.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACD06395; ACD06395; SbBS512_E2693.
GeneID	6272678.
KEGG	sbc:SbBS512_E2693.
PATRIC	18672446. VBIShiBoy129590_2982.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0285.
HOGENOM	HOG000019982.
KO	K11754.
OMA	VIAIVEH.
ProtClustDB	PRK10846.
Enzyme and pathway databases
BioCyc	SBOY344609:GI0O-2691-MONOMER.
Family and domain databases
Gene3D	3.40.1190.10. 1 hit. 3.90.190.20. 1 hit.
InterPro	IPR001645. Folylpolyglutamate_synth. IPR018109. Folylpolyglutamate_synth_CS. IPR004101. Mur_ligase_C. IPR013221. Mur_ligase_cen. [Graphical view]
PANTHER	PTHR11136. PTHR11136. 1 hit.
Pfam	PF02875. Mur_ligase_C. 1 hit. PF08245. Mur_ligase_M. 1 hit. [Graphical view]
PIRSF	PIRSF001563. Folylpolyglu_synth. 1 hit.
SUPFAM	SSF53244. Mur_ligase_C. 1 hit. SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMs	TIGR01499. folC. 1 hit.
PROSITE	PS01011. FOLYLPOLYGLU_SYNT_1. 1 hit. PS01012. FOLYLPOLYGLU_SYNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2TW97_SHIB3

Accession

Primary (citable) accession number: B2TW97

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	May 29, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)