B2TS68 (B2TS68_CLOBB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrodipicolinate synthase EMBL ACD24422.1
EC=4.2.1.52 EMBL ACD24422.1

Gene names

Name:	dapA EMBL ACD24422.1
Ordered Locus Names:	CLL_A2486

Organism

Clostridium botulinum (strain Eklund 17B / Type B) [Complete proteome] [HAMAP]

Taxonomic identifier

508765 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263
Subcellular location	Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Diaminopimelate biosynthesis SAAS SAAS005263 Lysine biosynthesis SAAS SAAS005263
Cellular component	Cytoplasm SAAS SAAS005263
Ligand	Schiff base SAAS SAAS005263
Molecular function	Lyase SAAS SAAS005263 EMBL ACD24422.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	diaminopimelate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	dihydrodipicolinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2TS68 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: AB039BD7FB695500	FASTA	292	31,959
	10 20 30 40 50 60 MSVFEGSGVA IVTPFNNEGV NYDKLKDLLE WHIKEGTDSI VICGTTGEAT TMTENEKKTV 70 80 90 100 110 120 IKFAVDVINN RIPVIAGTGS NNTLSAIEMS RYAESVGVDA ILVITPYYNK TSQKGLFKHF 130 140 150 160 170 180 KAVNDSVNIP IILYNVPSRT GVNITPKALV QIAELKNIVA IKEASGNISQ IMEMKSLCKD 190 200 210 220 230 240 KIDIYSGNDD QIVPIMSLGG KGVISVLANI IPNEVHTLTK KCLEGKFDEA LDIQLNRLKL 250 260 270 280 290 TNALFIETNP IPVKTAMNLM GFEVGSLRLP LCEMEDSNLD TLKTILKENK LI

References

[1]	"Complete sequence of Clostridium botulinum strain Eklund." Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001056 Genomic DNA. Translation: ACD24422.1.
RefSeq	YP_001886675.1. NC_010674.1.
3D structure databases
ProteinModelPortal	B2TS68.
ModBase	Search...
Protein-protein interaction databases
STRING	B2TS68.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6294064.
GenomeReviews	Gene locus CLL_A2486 in contig CP001056_GR.
KEGG	cbk:CLL_A2486.
PATRIC	19397792. VBICloBot123574_2401.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG358848.
OMA	CEMEDSN.
ProtClustDB	CLSK2327082.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002220. Dihydrodipicolinate_synth-like. IPR020625. Dihydrodipicolinate_synth_AS. IPR020624. Dihydrodipicolinate_synth_CS. IPR005263. Dihydrodipicolinate_synth_DapA. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01714.
PANTHER	PTHR12128. DHDPS. 1 hit.
Pfam	PF00701. DHDPS. 1 hit. [Graphical view]
PIRSF	PIRSF001365. DHDPS. 1 hit.
PRINTS	PR00146. DHPICSNTHASE.
TIGRFAMs	TIGR00674. DapA. 1 hit.
PROSITE	PS00665. DHDPS_1. 1 hit. PS00666. DHDPS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2TS68_CLOBB

Accession

Primary (citable) accession number: B2TS68

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)