B2TQ72 (B2TQ72_CLOBB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate synthase HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110

Gene names

Name:	aroB HAMAP MF_00110 EMBL ACD22746.1
Ordered Locus Names:	CLL_A3143

Organism

Clostridium botulinum (strain Eklund 17B / Type B) [Complete proteome] [HAMAP]

Taxonomic identifier

508765 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110
Cofactor	Divalent metal cations By similarity. HAMAP MF_00110 NAD By similarity. HAMAP MF_00110
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110
Subunit structure	Monomer By similarity. HAMAP MF_00110
Subcellular location	Cytoplasm By similarity HAMAP MF_00110.
Sequence similarities	Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00110
Cellular component	Cytoplasm HAMAP MF_00110
Ligand	NAD HAMAP MF_00110
Molecular function	Lyase HAMAP MF_00110 EMBL ACD22746.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2TQ72 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 8FDFA3D98910187E	FASTA	350	39,777
	10 20 30 40 50 60 MRELVVDLKE KSYSIIIKKG LINELSNEIN KLYKGKKIFI LTDENVNYHY GDKVKDLLIN 70 80 90 100 110 120 NGYDVKKMVL KPGEETKSFN TLPKIYNEFL DFKLTRSDLI ITLGGGVIGD LGGFAASTFL 130 140 150 160 170 180 RGIDFIQVPT SLLAQVDSSV GGKVAVDLDR GKNLVGSFYH PKVVLIDPDV LITLKDKFFK 190 200 210 220 230 240 DGMAEVIKYG CIKDLNFFYK LKEFKSKDEV LDNIEDIIYT CCNIKRIVVE NDEKDKGERM 250 260 270 280 290 300 LLNFGHTLGH AIESYYNFNK YTHGEAVGIG MYKIIKMSEE KGITPKGCAD EIKDILIQYS 310 320 330 340 350 LPYDIDIENL DEILETISLD KKNINNVLKI VLLDRIGQSF LKSTNIEFFK

References

[1]	"Complete sequence of Clostridium botulinum strain Eklund." Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001056 Genomic DNA. Translation: ACD22746.1.
RefSeq	YP_001887329.1. NC_010674.1.
3D structure databases
ProteinModelPortal	B2TQ72.
ModBase	Search...
Protein-protein interaction databases
STRING	B2TQ72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6295179.
GenomeReviews	Gene locus CLL_A3143 in contig CP001056_GR.
KEGG	cbk:CLL_A3143.
PATRIC	19399098. VBICloBot123574_3051.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG632303.
OMA	VMALEMS.
ProtClustDB	PRK00002.
Family and domain databases
HAMAP	MF_00110. DHQ_synthase. [Tree]
InterPro	IPR016037. DHQ_synth_AroB. [Graphical view]
KO	K01735.
PANTHER	PTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSF	PIRSF001455. DHQ_synth. 1 hit.
TIGRFAMs	TIGR01357. AroB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2TQ72_CLOBB

Accession

Primary (citable) accession number: B2TQ72

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)