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Protein
Submitted name:

Pyrophosphate-energized proton pump

Gene

CLL_A3052

Organism
Clostridium botulinum (strain Eklund 17B / Type B)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Enzyme and pathway databases

BioCyciCBOT508765:GJ4H-3040-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Pyrophosphate-energized proton pumpImported
Submitted name:
V-type H(+)-translocating pyrophosphataseImported (EC:3.6.1.1Imported)
Gene namesi
Ordered Locus Names:CLL_A3052Imported
ORF Names:CB17B2968Imported
OrganismiClostridium botulinum (strain Eklund 17B / Type B)Imported
Taxonomic identifieri935198 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001195 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2621HelicalSequence analysisAdd
BLAST
Transmembranei54 – 7219HelicalSequence analysisAdd
BLAST
Transmembranei78 – 9922HelicalSequence analysisAdd
BLAST
Transmembranei119 – 14628HelicalSequence analysisAdd
BLAST
Transmembranei152 – 16918HelicalSequence analysisAdd
BLAST
Transmembranei225 – 24319HelicalSequence analysisAdd
BLAST
Transmembranei249 – 26921HelicalSequence analysisAdd
BLAST
Transmembranei281 – 30424HelicalSequence analysisAdd
BLAST
Transmembranei310 – 33021HelicalSequence analysisAdd
BLAST
Transmembranei365 – 38420HelicalSequence analysisAdd
BLAST
Transmembranei390 – 41223HelicalSequence analysisAdd
BLAST
Transmembranei456 – 47520HelicalSequence analysisAdd
BLAST
Transmembranei487 – 50721HelicalSequence analysisAdd
BLAST
Transmembranei555 – 57319HelicalSequence analysisAdd
BLAST
Transmembranei579 – 59921HelicalSequence analysisAdd
BLAST
Transmembranei646 – 67429HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000007098.
KOiK15987.
OMAiNVMPALY.
OrthoDBiEOG6TXQSF.

Family and domain databases

HAMAPiMF_01129. PPase_energized_pump.
InterProiIPR004131. PPase-energised_H-pump.
[Graphical view]
PfamiPF03030. H_PPase. 1 hit.
[Graphical view]
PIRSFiPIRSF001265. H+-PPase. 1 hit.
TIGRFAMsiTIGR01104. V_PPase. 1 hit.

Sequencei

Sequence statusi: Complete.

B2TPW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLLYVSLIA GFIALIVVIF LAKDILKKSP GNEKMIEISG YIEEGAMAFL
60 70 80 90 100
RKEYSYLCVF IVVVAIAILV FLNYKTAIAF VVGALFSIIA GYIGMRIAVK
110 120 130 140 150
SNVRTAEAAK SGIKEALSVA FSGGTVMGLC VVGLGIIGLS IFSIVFDLNV
160 170 180 190 200
EYITGFGLGA SSIALFARVG GGIYTKAADV GADLVGKVEA GIPEDDPRNP
210 220 230 240 250
AVIADNVGDN VGDVAGMGAD LFESYVGSII SAITLGAVLV SSWGKEIVIF
260 270 280 290 300
PLVLSSIGIL ASLIGIVFVK SYKGDNPQKA LNLGSTISGA IVLVAGFIAC
310 320 330 340 350
KYLLGSYKIF LPVIAGLLIG LLIGKITEFY TSADYKSVKF IANESETGPA
360 370 380 390 400
TNIIAGLSVG MRSTVVPILL IAVGIIVSFF AIGGAKDTAL GLYGIALSAV
410 420 430 440 450
GMLSTTAITV AVDAYGPIAD NAGGIAEMCD LDDSIREITD KLDSVGNTTA
460 470 480 490 500
AIGKGFAIGS AALTALALFA SYSQIVNLET INLLNPLTLV GVLIGGMLPF
510 520 530 540 550
LFAALTMQSV GKAATQMVEE VRRQFKENDG ILKGTQKPDY SKCVEISTNA
560 570 580 590 600
ALKEMILPGI LAIAVPLLVG ILLGTEALAG VIGGGVVTGV MLAIMMANAG
610 620 630 640 650
GAWDNAKKYI ESGVHGGKGS YAHKAGVVGD TVGDPFKDTS GPSMNILIKL
660 670
MTIVSVVFAP VILKYGGILI NLFIK
Length:675
Mass (Da):69,724
Last modified:July 1, 2008 - v1
Checksum:iD98A300F27682602
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001056 Genomic DNA. Translation: ACD24512.1.
FR745875 Genomic DNA. Translation: CDH91957.1.
RefSeqiWP_012425260.1. NC_010674.1.

Genome annotation databases

EnsemblBacteriaiACD24512; ACD24512; CLL_A3052.
GeneIDi19965447.
KEGGicbk:CLL_A3052.
PATRICi19398918. VBICloBot123574_2961.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001056 Genomic DNA. Translation: ACD24512.1.
FR745875 Genomic DNA. Translation: CDH91957.1.
RefSeqiWP_012425260.1. NC_010674.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACD24512; ACD24512; CLL_A3052.
GeneIDi19965447.
KEGGicbk:CLL_A3052.
PATRICi19398918. VBICloBot123574_2961.

Phylogenomic databases

HOGENOMiHOG000007098.
KOiK15987.
OMAiNVMPALY.
OrthoDBiEOG6TXQSF.

Enzyme and pathway databases

BioCyciCBOT508765:GJ4H-3040-MONOMER.

Family and domain databases

HAMAPiMF_01129. PPase_energized_pump.
InterProiIPR004131. PPase-energised_H-pump.
[Graphical view]
PfamiPF03030. H_PPase. 1 hit.
[Graphical view]
PIRSFiPIRSF001265. H+-PPase. 1 hit.
TIGRFAMsiTIGR01104. V_PPase. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequence of Clostridium botulinum strain Eklund."
    Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Eklund 17B / Type BImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Eklund 17BImported.
  3. Shrivastava S., Brinkac L.M., Dodson R.J., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Eklund 17BImported.
  4. "Genomic and physiological variability within Group II (non-proteolytic) Clostridium botulinum."
    Stringer S.C., Carter A.T., Webb M.D., Wachnicka E., Crossman L.C., Sebaihia M., Peck M.W.
    BMC Genomics 14:333-333(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: B str. Eklund 17BImported.

Entry informationi

Entry nameiB2TPW1_CLOBB
AccessioniPrimary (citable) accession number: B2TPW1
Secondary accession number(s): U4PC04
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 13, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.