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Protein
Submitted name:

DNA topoisomerase

Gene

CLL_A2636

Organism
Clostridium botulinum (strain Eklund 17B / Type B)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseImported

Enzyme and pathway databases

BioCyciCBOT508765:GJ4H-2624-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA topoisomeraseImported
Submitted name:
Putative DNA topoisomeraseImported
Gene namesi
Ordered Locus Names:CLL_A2636Imported
ORF Names:CB17B2552Imported
OrganismiClostridium botulinum (strain Eklund 17B / Type B)Imported
Taxonomic identifieri935198 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001195 Componenti: Chromosome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 142141ToprimInterPro annotationAdd
BLAST

Phylogenomic databases

HOGENOMiHOG000086847.
KOiK03169.
OMAiRVMETCG.
OrthoDBiEOG60CWM6.

Family and domain databases

Gene3Di1.10.290.10. 1 hit.
1.10.460.10. 2 hits.
3.40.50.140. 1 hit.
InterProiIPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013826. Topo_IA_cen_sub3.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR006171. Toprim_domain.
[Graphical view]
PANTHERiPTHR11390. PTHR11390. 2 hits.
PfamiPF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSiPR00417. PRTPISMRASEI.
SMARTiSM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF56712. SSF56712. 1 hit.
PROSITEiPS50880. TOPRIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2TNL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVIIAEKP SVAKNIADAL NIKTRKDGYF KGEEYYITWA FGHLLQLYDA
60 70 80 90 100
KDYDENMKGW RMEKFPFIPE SFQYKVKCDN IDRTVEDKGA AKQINIIKSL
110 120 130 140 150
IEQEDVDGVI SATDFDREGQ VIADELFNYL NIQKPIYRLL LNEWTPDEVK
160 170 180 190 200
KGMGSLKENK EMQFLQDAGI GRQWTDWIIG INLTSVSTLK YKFEENKTIN
210 220 230 240 250
IGRVLLPTLK IIYDRDKEIE NFEATTYYKL TSTFKNSSNE EFDGLYYEKE
260 270 280 290 300
SEKFEDKSVL DNLVKLLDGT NATIIDKQTE KKKDYPPYLF NLSNLQGYIT
310 320 330 340 350
SKYKGWTSDK VLKVAQSLYE KKYTTYPRTA SVVLEESLED RARKVLNTLK
360 370 380 390 400
IGLPYEKDIK FIKTKRVFDN SKVESHSAIT PTYIKPNGLS KDEEIVYNAI
410 420 430 440 450
KNRFIMQFMP IAEFEETKIR LKPSNEEIQG EFISKGKVQL VEGWRVVEKI
460 470 480 490 500
DTKDTILPMV NVDEKVDIVS NKVNKVTKKP PKHHTEKTLL RVMETCGKGI
510 520 530 540 550
EGKEDSEEMM QSILNGFSIG TPATRAETIK KLKDIGYIGT KGKSLICTQL
560 570 580 590 600
GINIVEIFPV QELLDLEYTG RLESTLSDIE KGKFKKSDFM SLIYDFTNNA
610 620 630 640 650
VDKIKKDTSA LSKFKVELPE GAEEIGKCPV CGNSVIENEK NFGCTNWKNG
660 670 680 690 700
CKYTIWKDDK YISSFGKKVS KEMVVLLLKN GKVGFRNLKS KKGNTFSAYF
710
RYEKNEKTGY FNWNIEFI
Length:718
Mass (Da):82,671
Last modified:July 1, 2008 - v1
Checksum:i8A26115D11F65CDE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001056 Genomic DNA. Translation: ACD22284.1.
FR745875 Genomic DNA. Translation: CDH91541.1.
RefSeqiWP_012423151.1. NC_010674.1.

Genome annotation databases

EnsemblBacteriaiACD22284; ACD22284; CLL_A2636.
GeneIDi19964263.
KEGGicbk:CLL_A2636.
PATRICi19398090. VBICloBot123574_2549.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001056 Genomic DNA. Translation: ACD22284.1.
FR745875 Genomic DNA. Translation: CDH91541.1.
RefSeqiWP_012423151.1. NC_010674.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACD22284; ACD22284; CLL_A2636.
GeneIDi19964263.
KEGGicbk:CLL_A2636.
PATRICi19398090. VBICloBot123574_2549.

Phylogenomic databases

HOGENOMiHOG000086847.
KOiK03169.
OMAiRVMETCG.
OrthoDBiEOG60CWM6.

Enzyme and pathway databases

BioCyciCBOT508765:GJ4H-2624-MONOMER.

Family and domain databases

Gene3Di1.10.290.10. 1 hit.
1.10.460.10. 2 hits.
3.40.50.140. 1 hit.
InterProiIPR000380. Topo_IA.
IPR003601. Topo_IA_2.
IPR013497. Topo_IA_cen.
IPR013824. Topo_IA_cen_sub1.
IPR013826. Topo_IA_cen_sub3.
IPR023405. Topo_IA_core_domain.
IPR003602. Topo_IA_DNA-bd_dom.
IPR006171. Toprim_domain.
[Graphical view]
PANTHERiPTHR11390. PTHR11390. 2 hits.
PfamiPF01131. Topoisom_bac. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSiPR00417. PRTPISMRASEI.
SMARTiSM00437. TOP1Ac. 1 hit.
SM00436. TOP1Bc. 1 hit.
SM00493. TOPRIM. 1 hit.
[Graphical view]
SUPFAMiSSF56712. SSF56712. 1 hit.
PROSITEiPS50880. TOPRIM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequence of Clostridium botulinum strain Eklund."
    Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Eklund 17B / Type BImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Eklund 17BImported.
  3. Shrivastava S., Brinkac L.M., Dodson R.J., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Eklund 17BImported.
  4. "Genomic and physiological variability within Group II (non-proteolytic) Clostridium botulinum."
    Stringer S.C., Carter A.T., Webb M.D., Wachnicka E., Crossman L.C., Sebaihia M., Peck M.W.
    BMC Genomics 14:333-333(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: B str. Eklund 17BImported.

Entry informationi

Entry nameiB2TNL7_CLOBB
AccessioniPrimary (citable) accession number: B2TNL7
Secondary accession number(s): U4PMR6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: December 9, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.