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B2TNG3

- PYRB_CLOBB

UniProt

B2TNG3 - PYRB_CLOBB

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Protein

Aspartate carbamoyltransferase

Gene

pyrB

Organism
Clostridium botulinum (strain Eklund 17B / Type B)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. aspartate carbamoyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  3. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

BioCyciCBOT508765:GJ4H-2570-MONOMER.
UniPathwayiUPA00070; UER00116.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate carbamoyltransferaseUniRule annotation (EC:2.1.3.2UniRule annotation)
Alternative name(s):
Aspartate transcarbamylaseUniRule annotation
Short name:
ATCaseUniRule annotation
Gene namesi
Name:pyrBUniRule annotation
Ordered Locus Names:CLL_A2581
OrganismiClostridium botulinum (strain Eklund 17B / Type B)
Taxonomic identifieri935198 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001195: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Aspartate carbamoyltransferasePRO_1000088750Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi508765.CLL_A2581.

Structurei

3D structure databases

ProteinModelPortaliB2TNG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATCase/OTCase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0540.
HOGENOMiHOG000022685.
KOiK00609.
OMAiFDQYGKY.
OrthoDBiEOG61KBJZ.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_00001. Asp_carb_tr.
InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view]
PfamiPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSiPR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00670. asp_carb_tr. 1 hit.
PROSITEiPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2TNG3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIKDKHLIDP MDFTVEELEE IFKLAHEIIL DPEKFSHVCE GKILGTLFYE
60 70 80 90 100
PSTRTRFSFE AAMMRLGGKI LGFSEPNSSS ASKGESLSDT IKMVSIYTDI
110 120 130 140 150
IAMRHPKEGS AKVASLYSSV PIINAGDGGH QHPTQTLTDL LTIEMLKDGL
160 170 180 190 200
SNHTIGICGD LKYGRTVHSL IKAMSRYKGN KFLLISPKEL RIPDYIREEI
210 220 230 240 250
LRKNNIEFLE VETLEEVIDK VDILYMTRIQ KERFFNEEEY LRLRDSYILN
260 270 280 290 300
KEKMNLAKSD MIVMHPLPRV NEIACEVDYD KRAAYFKQAE YGMYARMALM

AKLLGVL
Length:307
Mass (Da):35,157
Last modified:July 1, 2008 - v1
Checksum:i373E089ACECEF97E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001056 Genomic DNA. Translation: ACD24851.1.
RefSeqiYP_001886770.1. NC_010674.1.

Genome annotation databases

EnsemblBacteriaiACD24851; ACD24851; CLL_A2581.
GeneIDi19963415.
KEGGicbk:CLL_A2581.
PATRICi19397980. VBICloBot123574_2495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001056 Genomic DNA. Translation: ACD24851.1 .
RefSeqi YP_001886770.1. NC_010674.1.

3D structure databases

ProteinModelPortali B2TNG3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 508765.CLL_A2581.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD24851 ; ACD24851 ; CLL_A2581 .
GeneIDi 19963415.
KEGGi cbk:CLL_A2581.
PATRICi 19397980. VBICloBot123574_2495.

Phylogenomic databases

eggNOGi COG0540.
HOGENOMi HOG000022685.
KOi K00609.
OMAi FDQYGKY.
OrthoDBi EOG61KBJZ.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00116 .
BioCyci CBOT508765:GJ4H-2570-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1370. 2 hits.
HAMAPi MF_00001. Asp_carb_tr.
InterProi IPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view ]
Pfami PF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view ]
PRINTSi PR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMi SSF53671. SSF53671. 1 hit.
TIGRFAMsi TIGR00670. asp_carb_tr. 1 hit.
PROSITEi PS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Clostridium botulinum strain Eklund."
    Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A., Smith T.J., Sutton G., Brettin T.S.
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Eklund 17B / Type B.

Entry informationi

Entry nameiPYRB_CLOBB
AccessioniPrimary (citable) accession number: B2TNG3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: November 26, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3