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Protein

Guanylate kinase

Gene

gmk

Organism
Clostridium botulinum (strain Eklund 17B / Type B)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 21ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotationImported
Ordered Locus Names:CLL_A1211Imported
OrganismiClostridium botulinum (strain Eklund 17B / Type B)Imported
Taxonomic identifieri935198 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001195 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 185Guanylate kinase-likeInterPro annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000037639.
KOiK00942.
OMAiYGTLKSE.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B2THR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDKKRGLLI VISGPSGAGK GTICKELLEK NDNLLLSVSA TTRSPRNGEI
60 70 80 90 100
DGVNYHFLCK EDFITRIEKN DFLEHAEVYG NYYGTPKSNV DKMLDSGRDV
110 120 130 140 150
ILEIDIQGAL KVKENTEEGV FIFILPPSME ELKQRIINRG SETPESLMKR
160 170 180 190 200
FKSAYKEINF VSKYNYAVVN DEVDIAVEKL EAIILAEKCR VDRLKHSILD
210
SKEDLIHEQL YD
Length:212
Mass (Da):24,101
Last modified:July 1, 2008 - v1
Checksum:iD869217A5DB3D704
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001056 Genomic DNA. Translation: ACD24674.1.
RefSeqiWP_012425412.1. NC_018648.1.

Genome annotation databases

EnsemblBacteriaiACD24674; ACD24674; CLL_A1211.
GeneIDi19964339.
KEGGicbk:CLL_A1211.
PATRICifig|935198.13.peg.1156.

Similar proteinsi

Entry informationi

Entry nameiB2THR7_CLOBB
AccessioniPrimary (citable) accession number: B2THR7
Secondary accession number(s): U4P422
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: October 25, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported