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B2TG13

- GLSA_BURPP

UniProt

B2TG13 - GLSA_BURPP

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Protein

Glutaminase

Gene

glsA

Organism
Burkholderia phytofirmans (strain DSM 17436 / PsJN)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631SubstrateUniRule annotation
Binding sitei113 – 1131SubstrateUniRule annotation
Binding sitei157 – 1571SubstrateUniRule annotation
Binding sitei164 – 1641SubstrateUniRule annotation
Binding sitei188 – 1881SubstrateUniRule annotation
Binding sitei240 – 2401SubstrateUniRule annotation
Binding sitei258 – 2581Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBPHY398527:GJEX-5605-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:Bphyt_5532
OrganismiBurkholderia phytofirmans (strain DSM 17436 / PsJN)
Taxonomic identifieri398527 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderia
ProteomesiUP000001739: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminasePRO_1000115694Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi398527.Bphyt_5532.

Structurei

3D structure databases

ProteinModelPortaliB2TG13.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B2TG13-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNYASILEQI RGDLQPFLGT GKVADYIPEL ATVPADSFGM AIVTASGEIF
60 70 80 90 100
RTGEADTRFS IQSISKLFAC TLAFQLLGDA LWERVGREPS GTAFNSLVQL
110 120 130 140 150
ESERGKPRNP FINAGALVVT DVLCRRFVQA ETALVEFMRR LTGETSIDYD
160 170 180 190 200
SRIAQSELQH AHRNRAMAHF MASFGNMEMP PEVVVDAYCR QCAISMSCVE
210 220 230 240 250
LAKAALFLTN HGVAPVTGER ILDTSSAKRL SALMLTCGTY DAAGDFVYRV
260 270 280 290 300
GLPAKSGVGG GIVAVLPGEM AACVWSPALD SNGNSAAGVL ALEWLTTYTG

QSIF
Length:304
Mass (Da):32,637
Last modified:July 1, 2008 - v1
Checksum:iF0CCE8C226881E16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001053 Genomic DNA. Translation: ACD19887.1.
RefSeqiWP_012427395.1. NC_010676.1.
YP_001889257.1. NC_010676.1.

Genome annotation databases

EnsemblBacteriaiACD19887; ACD19887; Bphyt_5532.
GeneIDi6279475.
KEGGibpy:Bphyt_5532.
PATRICi19205777. VBIBurPhy117947_1691.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001053 Genomic DNA. Translation: ACD19887.1 .
RefSeqi WP_012427395.1. NC_010676.1.
YP_001889257.1. NC_010676.1.

3D structure databases

ProteinModelPortali B2TG13.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 398527.Bphyt_5532.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACD19887 ; ACD19887 ; Bphyt_5532 .
GeneIDi 6279475.
KEGGi bpy:Bphyt_5532.
PATRICi 19205777. VBIBurPhy117947_1691.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci BPHY398527:GJEX-5605-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 2 of Burkholderia phytofirmans PsJN."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.
    , Nowak J., Sessitsch A., Lazarovits G., Compant S., Barka E., Tiedje J.
    Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17436 / PsJN.

Entry informationi

Entry nameiGLSA_BURPP
AccessioniPrimary (citable) accession number: B2TG13
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3