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B2TA52 (B2TA52_BURPP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Bphyt_7066
OrganismBurkholderia phytofirmans (strain DSM 17436 / PsJN) [Complete proteome] [HAMAP] EMBL ACD21354.1
Taxonomic identifier398527 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2291 By similarity HAMAP MF_01265
Binding site1331NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1991NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
B2TA52 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 4452E972607C3F96

FASTA27628,599
        10         20         30         40         50         60 
MRDAGYAGHH APVDVAMIGF GAIGQAVYRS VAADPTVRVS HVIVPERHMA SVREVVGDSV 

        70         80         90        100        110        120 
DVVASVSALS SQPHFALECA GHSALVDHVV PLLKAGTDCA VASIGALSDM LLLDALSAAA 

       130        140        150        160        170        180 
DEGDATLTLL SGAIGGVDAL AAAKLGGLDE VLYTGRKPPT GWLGTPAEQL CDLHTLKDEK 

       190        200        210        220        230        240 
VIFEGSAREA ARLYPKNANV AATIALAGLG LDHTTVRLIA DPNVTRNVHR IVARGAFGEM 

       250        260        270 
SLEMCGKPLP DNPKTSALTA YSAMRALRNR AARCVI

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References

[1]"Complete sequence of chromosome 2 of Burkholderia phytofirmans PsJN."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Nowak J., Sessitsch A., Lazarovits G., Compant S., Barka E., Tiedje J.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001053 Genomic DNA. Translation: ACD21354.1.
RefSeqYP_001890725.1. NC_010676.1.

3D structure databases

ProteinModelPortalB2TA52.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2TA52.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6278985.
GenomeReviewsGene locus Bphyt_7066 in contig CP001053_GR.
KEGGbpy:Bphyt_7066.
PATRIC19209117. VBIBurPhy117947_3353.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2TA52_BURPP
AccessionPrimary (citable) accession number: B2TA52
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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