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B2T9H3 (B2T9H3_BURPP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Bphyt_6781
OrganismBurkholderia phytofirmans (strain DSM 17436 / PsJN) [Complete proteome] [HAMAP] EMBL ACD21075.1
Taxonomic identifier398527 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length653 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS001017

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS001017

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS001017

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS001017

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS001017

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
B2T9H3 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: 600C5C8584A27515

FASTA65370,456
        10         20         30         40         50         60 
MRRMYEVRAR KFSYNGTTMY DLLKTIDDPA ALRRLDRRQL QPLADELRAF VLDSVSQTGG 

        70         80         90        100        110        120 
HLSSNLGTVE LTIALHYVFD TPRDRIVWDV GHQTYPHKIL TGRRDQMHTL RQLGGISGFP 

       130        140        150        160        170        180 
KRDESEYDTF GTAHSSTSIS AALGMAIASK LQGDNRTGIA VIGDGAMTAG MAFEAMNNAG 

       190        200        210        220        230        240 
VEDDVPLLVI LNDNDMSISP PVGALNRHLA RLMSGRFYAA ARAGVERVLR VAPPMLDLAR 

       250        260        270        280        290        300 
KLEEHAKGMI VPATLFEEFG FNYIGPIDGH DLDSLIPTLQ NIKELRGPQF LHVVTKKGQG 

       310        320        330        340        350        360 
YKLAEADPVL YHGPGKFNPA EGIKPATTPS KKTYTQVFGE WLCDAAELDA RVVGITPAMR 

       370        380        390        400        410        420 
EGSGMVEFEK RFPDRYFDVG IAEQHAVTFA GGLAAEGMKP VVAIYSTFLQ RAYDQLIHDV 

       430        440        450        460        470        480 
ALQNLPVVFA IDRAGLVGAD GATHAGAYDL AFLRCIPNMT VMAASDENEC RQMLYTALQQ 

       490        500        510        520        530        540 
PNPTAVRYPR GAGTGVATVK QMAALPLGKG EIRRETSQPA GKRIAILAFG TMVAPSLAAA 

       550        560        570        580        590        600 
EQLDATVANM RFVKPLDAAL VRQLAETHDA IVTIEEGCVM GGAGSACVEA LLESGVMRPV 

       610        620        630        640        650 
LQLGLPDRFI DHGDPAKLLA ACGLDAAGIT KSIRERFLSS GAVGGQSSVK RVA

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References

[1]"Complete sequence of chromosome 2 of Burkholderia phytofirmans PsJN."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Nowak J., Sessitsch A., Lazarovits G., Compant S., Barka E., Tiedje J.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001053 Genomic DNA. Translation: ACD21075.1.
RefSeqYP_001890446.1. NC_010676.1.

3D structure databases

ProteinModelPortalB2T9H3.
SMRB2T9H3. Positions 20-635.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2T9H3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6279294.
GenomeReviewsGene locus Bphyt_6781 in contig CP001053_GR.
KEGGbpy:Bphyt_6781.
PATRIC19208496. VBIBurPhy117947_3043.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG571647.
OMAEAMNAHA.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR001017. DH_E1.
IPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2T9H3_BURPP
AccessionPrimary (citable) accession number: B2T9H3
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info