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B2T808 (B2T808_BURPP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 HAMAP MF_00191
EC=1.17.1.2 HAMAP MF_00191
Gene names
Name:ispH2 HAMAP MF_00191
Ordered Locus Names:Bphyt_7036
OrganismBurkholderia phytofirmans (strain DSM 17436 / PsJN) [Complete proteome] [HAMAP] EMBL ACD21324.1
Taxonomic identifier398527 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) By similarity. HAMAP MF_00191

Catalytic activity

Dimethylallyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191

Isopentenyl diphosphate + NAD(P)+ + H2O = (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H. HAMAP MF_00191

Cofactor

Binds 1 3Fe-4S cluster By similarity. HAMAP MF_00191

Pathway

Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1. HAMAP MF_00191

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6. HAMAP MF_00191

Sequence similarities

Belongs to the IspH family. HAMAP MF_00191

Sequences

Sequence LengthMass (Da)Tools
B2T808 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: CA42475443E9AC12

FASTA31433,807
        10         20         30         40         50         60 
MRVILAQPRG FCAGVVRAIE IVDRALQQHG APVYVRHEIV HNRHVVDNLR QKGARFVEEL 

        70         80         90        100        110        120 
DEVPQGAVAI FSAHGVAQTV ERDAEARGLD VLDATCPLVT KVHVQGRQYV GAGRTLILIG 

       130        140        150        160        170        180 
HAGHPEVEGT IGQIPGKVLL VQSEAEVAHL DLPVDTPLAY VTQTTLSVDD TRGIIDALLR 

       190        200        210        220        230        240 
RFTDIVGPDT RDICYATQNR QAAVRELSKQ VDVLLVVGAT NSSNSNRLRE IGSESGVASY 

       250        260        270        280        290        300 
LVADGSEVKP EWFANVQTVG ITAGASAPEE MVKNVIDALS ALGPVDVTTM AGREEKVEFK 

       310 
LPSKLMQPLA AREV

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia phytofirmans PsJN."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Nowak J., Sessitsch A., Lazarovits G., Compant S., Barka E., Tiedje J.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001053 Genomic DNA. Translation: ACD21324.1.
RefSeqYP_001890695.1. NC_010676.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2T808.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6278040.
GenomeReviewsGene locus Bphyt_7036 in contig CP001053_GR.
KEGGbpy:Bphyt_7036.
PATRIC19209055. VBIBurPhy117947_3322.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG335228.
OMAHNQGKRY.
ProtClustDBPRK01045.

Family and domain databases

HAMAPMF_00191. IspH.
[Tree]
InterProIPR003451. LytB.
[Graphical view]
KOK03527.
PfamPF02401. LYTB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00216. IspH_lytB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2T808_BURPP
AccessionPrimary (citable) accession number: B2T808
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info