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B2T313 (B2T313_BURPP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase HAMAP MF_01174
Gene names
Name:astD HAMAP MF_01174
Ordered Locus Names:Bphyt_1561
OrganismBurkholderia phytofirmans (strain DSM 17436 / PsJN) [Complete proteome] [HAMAP] EMBL ACD15974.1
Taxonomic identifier398527 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Ontologies

Keywords
   Biological processArginine metabolism HAMAP MF_01174
   LigandNAD HAMAP MF_01174
   Molecular functionOxidoreductase HAMAP MF_01174
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine catabolic process to glutamate

Inferred from electronic annotation. Source: HAMAP

   Molecular functionsuccinylglutamate-semialdehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding221 – 2266NAD By similarity HAMAP MF_01174

Sites

Active site2441 By similarity HAMAP MF_01174
Active site2781 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
B2T313 [UniParc].

Last modified July 1, 2008. Version 1.
Checksum: F7C59EC2A500C010

FASTA48751,846
        10         20         30         40         50         60 
MSELFIDGEW AAGTGPAFAS HNPGTGAAVW EGNSASADDV DRAVRSARRA FPAWSALSLD 

        70         80         90        100        110        120 
ERCGVVRRFA ALVTERKEAL AEAIGRETGK PLWEARTEAA SMAAKVEISI QAYNERTGEK 

       130        140        150        160        170        180 
RSAMADGTAV LRHRPHGVVA VFGPYNFPGH LPNGHIVPAL IAGNAVVFKP SELAPGVAAL 

       190        200        210        220        230        240 
TVQIWRDAGL PTGVLNLVQG EKDTGIALAN HRQIDGLFFT GSSDTGTLLH KQFGGRPEIV 

       250        260        270        280        290        300 
LALEMGGNNP LVIGPVADVD AAVHHTIQSA FLSAGQRCTC ARRIFVPNDA GGDRFMERFT 

       310        320        330        340        350        360 
EVTSRITVGE YNADPQPFMG AVISARAASR LVAAQERLLA DGAKALLKME QRDPKLGFVT 

       370        380        390        400        410        420 
PAILDVTNVK NLPDEEHFGP LAQIIRYGSF NEALEQANDT EFGLSAGLLA DDEALWTHFQ 

       430        440        450        460        470        480 
RTIRAGIVNW NRPTNGASSG APFGGPGRSG NHRPSAYYAA DYCAFPMASV ESAQLQMPAS 


VSPGLQF

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References

[1]"Complete sequence of chromosome 1 of Burkholderia phytofirmans PsJN."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Nowak J., Sessitsch A., Lazarovits G., Compant S., Barka E., Tiedje J.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001052 Genomic DNA. Translation: ACD15974.1.
RefSeqYP_001895198.1. NC_010681.1.

3D structure databases

ProteinModelPortalB2T313.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2T313.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6281826.
GenomeReviewsGene locus Bphyt_1561 in contig CP001052_GR.
KEGGbpy:Bphyt_1561.
PATRIC19213202. VBIBurPhy117947_5380.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG752218.
OMAMTQRDPR.
ProtClustDBPRK09457.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2T313_BURPP
AccessionPrimary (citable) accession number: B2T313
Entry history
Integrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info