B2T2I8 (B2T2I8_BURPP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 2 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-2 HAMAP MF_01902
Ordered Locus Names:	Bphyt_1384

Organism

Burkholderia phytofirmans (strain DSM 17436 / PsJN) [Complete proteome] [HAMAP] EMBL ACD15799.1

Taxonomic identifier

398527 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	1193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2T2I8 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: F360D59BD76930AC	FASTA	1,193	132,911
	10 20 30 40 50 60 MPPTQPSLLV QQPLATQLPA YAELHCLTNF SFLRGASHPH ELVEQAMSRG YSALAITDEC 70 80 90 100 110 120 SLAGVVRAHT ALKEIKTERE RQQKEREDKA NTAQSEAPSE DGTQIEASQQ ETAPQETAEA 130 140 150 160 170 180 EAPKPLPHLI IGSELNLTDE TGDPFCTLVA LATNRNGYGN LSELITLARS RADKGSYRLG 190 200 210 220 230 240 PSDFTASLPH LAHLKTLPDC VLMLVPQRTA TLSHTLRCAH WLASFAAQRA WIALELWQTG 250 260 270 280 290 300 SDDLQIDALR MISKASGLPL VAAGGVLMHA RSRKPLQDTM TAIGLVTPLS QCGHALEANA 310 320 330 340 350 360 ERHMRTRVRL GKLYPRDTLE ETLRIAALCR FSLDELKYEY PEELVPAGES PSSYLRKLVM 370 380 390 400 410 420 AGAMERWPKG IDLKRIGQIE KELGLIADLK YEKYFLTVHD IVSFARSRNI LCQGRGSAAN 430 440 450 460 470 480 SIVCYCLHVT EIDPVHMNML IERFISRARN EPPDIDVDFE HQRREEVIQY IYTKYGRHRA 490 500 510 520 530 540 ALTASLITYH ARSALKDVGK ALGLEVSLIE RISKSQQWWD GTDAVAKYLA EAGFDANSHI 550 560 570 580 590 600 TQNLIRLTKE LRAFPRHLSQ HVGGFVIAKD KLSRLVPIEN ATMKDRSVIE WDKDDIDALK 610 620 630 640 650 660 LLKVDVLALG MLSAIRRALE FVALRRGFPK FSVQDIPRED RAVYEMCGHA DTIGVFQIES 670 680 690 700 710 720 RAQQSMLPRL KPNKYYDLVI EVAIVRPGPI QGGMVHPYLR RKQGLEAVDY AKDELRPVLE 730 740 750 760 770 780 RTLGVPIFQE QVMHLAMVAA KYTGEQADQL RRAMAAWRRS GNLAKYQKDL NERMLKRGYE 790 800 810 820 830 840 QEFIDRICKQ IEGFGEYGFP ESHAASFALL VYLSAWLKRY EPAAFLAGLL NSQPLGFYSP 850 860 870 880 890 900 SQLVQDAKRH GVEVLPPDVT LSDWESTFER RGHEGQRISA DETCLHRQQA VLSAQQLRDL 910 920 930 940 950 960 SLRRLTVSRT VRRAAQRLTA RVFQPSHTYG ARGPAVRIGM HLIKGFSQAA AERIMAARNE 970 980 990 1000 1010 1020 APFTDVDDLA RRAALTRRDL EALAAANALV SIAGHRREAW WAVTAQHTVP KLLRDAPIAE 1030 1040 1050 1060 1070 1080 APLMLPQAAE SREIVDDYAS LGLTLNRHPL ALLRARLAQH RFRTAAELAA CQHGTLARAC 1090 1100 1110 1120 1130 1140 GIVTVRQRPG TANGTVFVSI EDETGSINVI VWPSLVEKQR KVLLGASLLA VYGVLQRDDG 1150 1160 1170 1180 1190 VATGGDQAGN GVSANQAKGK RKNKGEVIHL VAHRLEDHSE WLGELATASR DFH

References

[1]

"Complete sequence of chromosome 1 of Burkholderia phytofirmans PsJN." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Nowak J., Sessitsch A., Lazarovits G., Compant S., Barka E., Tiedje J. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001052 Genomic DNA. Translation: ACD15799.1.
RefSeq	YP_001895023.1. NC_010681.1.
3D structure databases
ProteinModelPortal	B2T2I8.
ModBase	Search...
Protein-protein interaction databases
STRING	B2T2I8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6281226.
GenomeReviews	Gene locus Bphyt_1384 in contig CP001052_GR.
KEGG	bpy:Bphyt_1384.
PATRIC	19212822. VBIBurPhy117947_5191.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	CLSK2314123.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2T2I8_BURPP

Accession

Primary (citable) accession number: B2T2I8

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)