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Protein

RNA pyrophosphohydrolase

Gene

rppH

Organism
Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) (Burkholderia phytofirmans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.UniRule annotationSAAS annotation

Cofactori

a divalent metal cationUniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
RNA pyrophosphohydrolaseUniRule annotationSAAS annotation (EC:3.6.1.-UniRule annotation)
Alternative name(s):
(Di)nucleoside polyphosphate hydrolaseUniRule annotation
Gene namesi
Name:rppHUniRule annotation
Synonyms:nudHUniRule annotation
Ordered Locus Names:Bphyt_3444Imported
OrganismiParaburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) (Burkholderia phytofirmans)Imported
Taxonomic identifieri398527 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeParaburkholderia
Proteomesi
  • UP000001739 Componenti: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi398527.Bphyt_3444

Structurei

3D structure databases

ProteinModelPortaliB2SYU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 149Nudix hydrolaseInterPro annotationAdd BLAST144

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi38 – 59Nudix boxUniRule annotationAdd BLAST22

Sequence similaritiesi

Belongs to the Nudix hydrolase family. RppH subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105EJF Bacteria
COG0494 LUCA
HOGENOMiHOG000066723
KOiK08311
OMAiLPGLEWQ
OrthoDBiPOG091H0392

Family and domain databases

CDDicd03671 Ap4A_hydrolase_plant_like, 1 hit
HAMAPiMF_00298 Nudix_RppH, 1 hit
InterProiView protein in InterPro
IPR020476 Nudix_hydrolase
IPR015797 NUDIX_hydrolase-like_dom_sf
IPR020084 NUDIX_hydrolase_CS
IPR000086 NUDIX_hydrolase_dom
IPR022927 RppH
PfamiView protein in Pfam
PF00293 NUDIX, 1 hit
PRINTSiPR00502 NUDIXFAMILY
SUPFAMiSSF55811 SSF55811, 1 hit
PROSITEiView protein in PROSITE
PS51462 NUDIX, 1 hit
PS00893 NUDIX_BOX, 1 hit

Sequencei

Sequence statusi: Complete.

B2SYU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDREGFRPN VGIILLNAHN EVFWGKRLRE HSWQFPQGGI KYGETPVQAM
60 70 80 90 100
YRELHEETGL LPEHVKVIGR TRDWLRYEVP DKFIKREVRG HYRGQKQIWF
110 120 130 140 150
LLRMVGRDCD ICLRATDHPE FDAWRWNEYW VPLDCVIEFK RDVYQLALTE
160 170 180 190 200
LSRFMRRAAP RAEKPGGHHG PRYPRIASSM ESPPDSTVMT VTSVTTVSIE
210 220 230 240
TSVHVTIASD CGPGSASTAE VDAAPDHEDE SAGETAGSLF RPGVRN
Length:246
Mass (Da):28,144
Last modified:July 1, 2008 - v1
Checksum:i9F49C4CB739B176A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001052 Genomic DNA Translation: ACD17834.1
RefSeqiWP_012434397.1, NC_010681.1

Genome annotation databases

EnsemblBacteriaiACD17834; ACD17834; Bphyt_3444
KEGGibpy:Bphyt_3444

Similar proteinsi

Entry informationi

Entry nameiB2SYU9_PARPJ
AccessioniPrimary (citable) accession number: B2SYU9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: April 25, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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