B2SYS4 (B2SYS4_BURPP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase 1 HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE1 HAMAP MF_00222
Ordered Locus Names:	Bphyt_3419

Organism

Burkholderia phytofirmans (strain DSM 17436 / PsJN) [Complete proteome] [HAMAP] EMBL ACD17809.1

Taxonomic identifier

398527 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia

Protein attributes

Sequence length	287 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222
Ligand	NADP HAMAP MF_00222
Molecular function	Oxidoreductase HAMAP MF_00222
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	132 – 136	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	71	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	B2SYS4 [UniParc]. Last modified July 1, 2008. Version 1. Checksum: 18B7D6831D1743DB	FASTA	287	29,964
	10 20 30 40 50 60 MSTQDSRDRY AVIGNPVGHS KSPFIHGRFA AQTGEAVEYG HLLAPVDAFV PHVRAFIDAG 70 80 90 100 110 120 GRGLNVTVPF KLDAHAFADT LSPRAAAAGA VNTLRFDANG IYGDNTDGFG LVRDIEVNLG 130 140 150 160 170 180 VSLKGARILL LGAGGAARGV VLPMLDRAPH TLTIVNRTAE KAEALVAQFA QAARDAACQL 190 200 210 220 230 240 SGGSARAIEA GTYDVIVNAT AGSLDASLPE CDDRAFGNGT LAYDMMYGAH PTVFMEHARK 250 260 270 280 LGARGADGLG MLVEQAAESF YVWRGVRPDG APVLAELRAL LTAPSHA

References

[1]

"Complete sequence of chromosome 1 of Burkholderia phytofirmans PsJN." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Nowak J., Sessitsch A., Lazarovits G., Compant S., Barka E., Tiedje J. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001052 Genomic DNA. Translation: ACD17809.1.
RefSeq	YP_001897033.1. NC_010681.1.
3D structure databases
ProteinModelPortal	B2SYS4.
ModBase	Search...
Protein-protein interaction databases
STRING	B2SYS4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6282361.
GenomeReviews	Gene locus Bphyt_3419 in contig CP001052_GR.
KEGG	bpy:Bphyt_3419.
PATRIC	19217386. VBIBurPhy117947_7440.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553408.
OMA	VVFGNPI.
ProtClustDB	PRK00258.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2SYS4_BURPP

Accession

Primary (citable) accession number: B2SYS4

Entry history

Integrated into UniProtKB/TrEMBL:	July 1, 2008
Last sequence update:	July 1, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)