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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) (Burkholderia phytofirmans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Bphyt_0473
OrganismiParaburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) (Burkholderia phytofirmans)
Taxonomic identifieri398527 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeParaburkholderia
Proteomesi
  • UP000001739 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953451 – 596Arginine--tRNA ligaseAdd BLAST596

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi398527.Bphyt_0473

Structurei

3D structure databases

ProteinModelPortaliB2SWV4
SMRiB2SWV4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi139 – 149"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6202 hits
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B2SWV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPAHKLTLE TLLAETVKQV ATASQGASEA AFVSPAITLE RPKVAAHGDV
60 70 80 90 100
ACNVAMQLAK PLRANPRQLA QQIVDALLAQ PQAKGLVEAA EVAGPGFINL
110 120 130 140 150
RLAAAAKQAV IAAVFAEKEA FGRSQRDAGK HVLIEFVSAN PTGPLHVGHG
160 170 180 190 200
RQAALGDALS NVLASQGYDV HREFYYNDAG VQIQTLALST QARARGLAPG
210 220 230 240 250
DAGWPASAYN GEYIAEIARD YLNGVTVAAS DGEPVTGARD VEDLEAIRRF
260 270 280 290 300
AVAYLRREQD MDLQAFGVKF DQYYLESSLY KEGRVEKTVE ALIAAGKTYE
310 320 330 340 350
QEGALWLRTT DDGDDKDRVM RKTDGTYTYF VPDVAYHVAK WERGFTKVIN
360 370 380 390 400
VQGSDHHGTI ARVRAGLQGL GVGIPKGYPD YILHKMVTVM RNGEEVKISK
410 420 430 440 450
RAGSYVTVRD LIEWSGGATP GSEAAVDLID EETIRRGRDA VRFFLISRKA
460 470 480 490 500
DTEFVFDIDL ALKQNDENPV HYVQYAHARI CSVIAECKAR YSTDESTLAD
510 520 530 540 550
VDVSPLTSER AMALLNKLAE FPDMLQHAAD ELAPHAVAFY LRDLAGEFHS
560 570 580 590
FYNDRTERVL VDDAAERNAR VALLAATRQV LANGLATIGV SAPVKM
Length:596
Mass (Da):64,841
Last modified:July 1, 2008 - v1
Checksum:i01555E30149643B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001052 Genomic DNA Translation: ACD14898.1
RefSeqiWP_012431541.1, NC_010681.1

Genome annotation databases

EnsemblBacteriaiACD14898; ACD14898; Bphyt_0473
KEGGibpy:Bphyt_0473

Similar proteinsi

Entry informationi

Entry nameiSYR_PARPJ
AccessioniPrimary (citable) accession number: B2SWV4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 1, 2008
Last modified: April 25, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome