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B2SQE6

- B2SQE6_XANOP

UniProt

B2SQE6 - B2SQE6_XANOP

Protein

Alanine racemase

Gene

alr

Organism
Xanthomonas oryzae pv. oryzae (strain PXO99A)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (01 Jul 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei33 – 331Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei129 – 1291SubstrateUniRule annotation
    Active sitei253 – 2531Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei301 – 3011Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciXORY360094:GI45-4594-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:PXO_03074Imported
    OrganismiXanthomonas oryzae pv. oryzae (strain PXO99A)Imported
    Taxonomic identifieri360094 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000001740: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei33 – 331N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi360094.PXO_03074.

    Structurei

    3D structure databases

    ProteinModelPortaliB2SQE6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031446.
    KOiK01775.
    OMAiLWQLEAI.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B2SQE6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRPAQASIDL EALRHNYRLA KRLGGSKALA VVKADAYGHG AVRCAQALEP    50
    EADGFAVACI EEALELRQAG IRAPILLLEG FFEHDELRLI AEHDLWTVAA 100
    TPQQVRALAA FQSPRPLRVW LKMDSGMHRL GLSPEDFRAA WLRLCGLPQI 150
    ASLVLMTHLA RADELDCSRT DEQAVAFALS AGGMRAETSL RNSPGLLGWP 200
    ALRNDWSRPG LMLYGANPFP QDTENTAQLR PVMTLRSRII LVRDLPVGEP 250
    VGYGARFVAE RPTRVGVVAM GYADGYPQFA PNGTPVLVDG QVCPLIGRVS 300
    MDMLTVDLTD HPQAAIGATV QLWGQAPRVG PLATQCNVSA YQLLCGLKRV 350
    PRTYVGSAAV GEVAAR 366
    Length:366
    Mass (Da):39,627
    Last modified:July 1, 2008 - v1
    Checksum:iF9B6871969A4FA1C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000967 Genomic DNA. Translation: ACD61144.1.
    RefSeqiYP_001915676.1. NC_010717.1.

    Genome annotation databases

    EnsemblBacteriaiACD61144; ACD61144; PXO_03074.
    GeneIDi6308113.
    KEGGixop:PXO_03074.
    PATRICi24128776. VBIXanOry73153_4726.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000967 Genomic DNA. Translation: ACD61144.1 .
    RefSeqi YP_001915676.1. NC_010717.1.

    3D structure databases

    ProteinModelPortali B2SQE6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 360094.PXO_03074.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACD61144 ; ACD61144 ; PXO_03074 .
    GeneIDi 6308113.
    KEGGi xop:PXO_03074.
    PATRICi 24128776. VBIXanOry73153_4726.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031446.
    KOi K01775.
    OMAi LWQLEAI.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci XORY360094:GI45-4594-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PXO99AImported.

    Entry informationi

    Entry nameiB2SQE6_XANOP
    AccessioniPrimary (citable) accession number: B2SQE6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 1, 2008
    Last sequence update: July 1, 2008
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3